宫腔镜治疗宫颈上皮内瘤变疗效分析

Curative effect analysis of hysteroscopy in treatment of cervical intraepithelial neoplasia

目的:探讨宫腔镜治疗宫颈上皮内瘤变(CIN)的临床疗效。方法:将宫颈上皮内瘤变患者159例分成A组83例和B组76例,A组行宫腔镜下锥形电切术,B组同期行宫颈冷刀锥切术(CKC),切除组织均送病理。比较两组的手术时间、术中出血量、切口愈合时间、术后切缘阳性率、术后病理吻合率及随访结果。结果:两组的手术时间、术中出血量、术后切口愈合时间及术后切缘阳性率比较,差异均有统计学意义(P<0.05),而病理结果及随诊各项观察指标比较差异无统计学意义(P>0.05)。结论:宫腔镜电切手术时间短,出血量少,切缘阳性率低,术后愈合快,是一种治疗宫颈上皮内瘤变的较好方法。

Objective： To evaluate the therapeutic effect of hysteroscopy in the treatment of cervical intraepithelial neoplasia （CIN） . Methods： All 159 of cervical intraepithelial neoplasia patients were randomly divided into group A （83 cases） and group B （76 cases） . The hysteroscopy electrosection was used in group A and cold knife conization was used in group B at the same period. The resected specimens were sent for pathological diagnosis. The operation time, bleeding volume, wound healing time, cut positive margin rate, postop- erative pathologic matching rate and follow - up results were compared between the two groups. Results ： Statistically significant differences were found in the operative time, bleeding volume and wound healing time and cut positive margin rate between the two groups （ P 〈 0.05 ） . There were no difference in results of pathology and follow - up between the two groups （ P 〉 0. 05 ） . Conclusion ： Hysteroscopy eleetrosection （TCRC） with shorter operation time, more less bleeding volume, shorter wound healing time, lower cut positive margin rate, is a better therapy way of CIN, and has clinical diagnosis value.