790例流行性感冒样病例临床特征分析

Analysis on Clinical Characteristics of 790 Influenza-like Illness Cases

目的了解甲型H1N1流行性感冒(流感)(甲流)病例与其他流感样病例(Influenza-like Illness,ILI)的临床特征。方法以疫苗上市后10个县(区)监测点的在校师生作为监测对象,对2009年11月20日～2010年5月31日发生的ILI临床症状进行流行病学问卷调查。结果调查的790例ILI的主要症状为发热、咳嗽、咽痛。甲流患者的高热(>39.0℃)发生率高于其他ILI,两组发热率的差异有统计学意义(2=6.57,P=0.01)。甲流病例与其他ILI除发热外,其他临床特征基本相同,差异无统计学意义。男性各症状的发生率差异均无统计学意义;女性ILI中,甲流患者(14例)咽痛(2=4.17,P<0.05)、咳嗽/咳痰(2=4.40,P<0.05)的发生率高于其他ILI(164例),差异有统计学意义。不同年龄ILI中,甲流与其他ILI各症状发生率差异均无统计学意义。结论 ILI中,甲流患者与其他ILI的临床特征差别不大。

Objective This study was to analyze the differences in clinical features between influenza virus A （H1N1 ） and influenza-like illness （ILI）. Methods With an active surveillance of ILI in 10 county level vaccine post-marketing surveillance sites, a questionnaire survey for clinical characteristics was conducted among all ILI Results The most common symptoms of ILI were cough and sore throat.There were no statistical differences in influenza virus A （HIN1） and ILI. However the incidence of pharyngalgia （X^2 =4.17, P〈0.05 ） and cough/expectoration （X^2=4.40, P〈0.05 ） of influenza A （ H1N1 ） was higher than ILI in females. There was basically the same incidence of cough/expectoration of ILI among different age group. Conclusion There were differences in gender between influenza A （H,N,） and other ILI.