摘要
[目的]研究甲基磺草酮的重要中间体2-硝基-4-甲砜基苯甲酸的合成新方法。[方法]以邻硝基甲苯为起始原料,经过磺化、氧化,最后得到邻硝基对甲砜基苯甲酸的工艺路线。讨论合成工艺路线的优化及条件。[结果]制备成本降低至5万元/吨。[结论]该工艺简单经济,适合工业化生产。
A novel synthetic method of the important intermediate compound of mesotrione,4-（methylsulfonyl）-2-nitrobenzoic acid,was reported in detail.[Methods] The compound was synthesized from o-nitrobenzene by three steps including sulfonation,oxidation,and so on.The reaction condition was optimized.[Results] The cost of production was induced to $50？000 per ton.[Conclusions] Its preparing process is simple and low-cost,which is suitable for industrial scale manufacture.
出处
《农药》
CAS
CSCD
北大核心
2013年第3期174-177,共4页
Agrochemicals
