干部病房132例多重耐药菌感染临床分析

Clinical analysis of 132 cases of multi-resistant bacteria infection in the senior cadres ward

目的探讨多重耐药菌感染的临床特点,为其防治提供科学依据。方法对2007年1月～2011年12月解放军117医院干部病房,共132例多重耐药菌感染患者的临床特点、病原菌构成、药物敏感率进行回顾性分析。结果全部病例均为院内感染,以肺部感染为主,其发生与年龄、基础疾病、住院时间、高档抗生素的使用等相关。主要病原菌为假单胞菌属、葡萄球菌属和鲍曼不动杆菌、肺炎克雷伯菌。结论多重耐药菌感染多发生于老年人,治疗困难,预后极差。加强住院期管理及抗生素的合理使用是预防多重耐药菌感染的重要手段。

Objuctive To find out the clinical features of multi-resistant bacteria infection in the elderly wards, so as to provide bases for prevention. Methods One hundred and thirty-two cases with multi-resistant bacteria infection from Jan 2007 to 2011 in the Central Hospital of Mainyang were retrospectively analyzed, including clinical features, pathogen constitution,medicine sensitive materials,etc. Results All patients were confirmed to have acquired nosocomial infection,most of which were pulmonary. The occurrence rate of multi-resistant bacteria infection was associated with age, disease, hospitalization, mechanical ventilation time and long-term use of antibiotics,etc. The main pathogens included Staphylococcus aureus,Pseudomonas, Baoman aeinetobater,and Cray borrelia bacteria pneumonia. Conclusions Multi-resistant bacteria infections are most prevalent among the elders. The clinical treatment is very difficult and the prognosis is poor. We should improvement the management of hospital as well as strengthen the supervision of the rational use of antibiotics.