新生儿坏死性小肠结肠炎26例临床分析

Neonatal Necrotizing Enterocolitis: A Clinical Analysis of 26 Cases

目的:分析新生儿坏死性小肠结肠炎(NEC)的临床特征、早期诊断、治疗方法及结局,以提高对该病的认识,做到早期诊断,早期治疗。方法:对我院2011年1月至2011年12月收治的26例NEC患儿资料进行回顾性分析。结果:本组资料中,治愈或好转22例(84.6%),死亡4例(15.4%),其中由于病情严重或家庭经济原因而自动放弃治疗者3例,经随访确认后归入死亡组;患儿住院时间为1～67 d,平均(32.9±37.2)d。结论:提高对NEC的认识,减少处于NECⅢ期病例是目前NEC防治过程中的关键。新生儿急救转运系统的建立和推广对降低网络覆盖地区的新生儿病死率,提高生存质量有重要意义。

Objective： To analyze the clinical features, early diagnosis, treatment and outcomes of NEC, and to improve the knowledge of the disease. Methods： Retrospective analysis of the 26 cases of neonatal necrotizing enterocolitis from January 2011 to December 2011 in Hubei Province Maternal and Child Health Hospital. Results： In the 26 cases, 22 cases were cured or improved （84.6%）, and 4 cases were dead （15.4%）. In the dead cases, 3 cases gave up the treatment due to serious illness or family economic stress, which were confirmed and classified into the death group after a follow-up. The length of hospital stay ranged from 1 to 67 days, with an average of （32.9±37.2） days. Conclusions： Improvement of the knowledge of NEC and reduction of NEC stage Ⅲ cases are the key to prevention and cure NEC. Establishment and promotion of the neonatal emergency transport system have a far-reaching significance to reduce the regional neonatal mortality, and improve the quality of life.