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不同血液净化治疗模式对尿毒症患者毒素清除的效果观察 被引量:11

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摘要 目的:观察不同血液净化治疗模式对尿毒症患者小分子毒素尿素氮(BUN)、血磷及中分子毒素β2微球蛋白(β2-MG)、全段甲状旁腺激素(iPTH)清除的效果。方法:选择在我中心行维持性血液净化治疗3个月以上且病情稳定的尿毒症61例,分为血液透析组(HD)23例,血液透析滤过组(HDF)21例,血液透析联合血液灌流组(HD+HP)17例。单次治疗前后分别检测血BUN、血磷、β2-MG、iPTH,比较各组对毒素的清除效果。结果:治疗后,3组血BUN、血磷水平均较治疗前显著降低(P<0.05);HD组血β2-MG、iPTH水平与治疗前比较差异不显著(P>0.05),HDF组和HD+HP组血β2-MG、iPTH水平均较治疗前显著降低(P<0.05)。结论:血液透析滤过和血液灌流比单纯血液透析能更好地清除尿毒症患者体内的中分子毒素。
出处 《人民军医》 2013年第3期311-312,314,共3页 People's Military Surgeon
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