经气管镜吸痰和灌洗治疗重症COPD临床分析

Clinical analysis of fiberoptic bronchoscopic sputum suction and lavage in the treatment of patients with severe chronic obstructive pulmonary disease

目的探讨支气管镜吸痰和灌洗对重症COPD的治疗价值。方法对30例重症COPD患者进行支气管镜吸痰和灌洗(BL)治疗。治疗前、治疗后10分钟和治疗后5小时测定肺功能[第1秒用力呼气容积占预计值的百分比(FEV1.0%)],治疗时监测血氧饱和度(SaO2)的变化,观察临床表现。结果治疗后10分钟FEV1.0%无显著变化(P>0.05),治疗后5小时FEV1.0%由0.42±0.12升至0.59±0.19,较前显著增高(P<0.05)。结论经支气管镜吸痰和灌洗治疗是针对重症COPD积极的治疗方法。

Objective To investigate the curative value of bronchial lavage （BL） and aspiration of sputum in the treatment of pa- tients with severe chronic obstructive pulmonary disease （COPD）. Methods 30 patients with severe obstructive pulmonary disease were given bronchial lavage and aspiration of sputum treatment. Lung function was tested before the treatment, 10 minutes and 5 hours after the treatment （ forced expiratory volume in the first second percentages to prediction （ FEV1.0 % ） ）. The change of oxygen saturation （ SaO2 ） and clinical manifestations were also observed. Results 10 minutes after the treatment, FEVI.0% had no significant change （P 〉 0. 05）. 5 hours after the treatment, FEVI.0% increased from 0. 42 ±0. 12 to 0. 59 ±0. 19, which was significantly higher than before （P 〈 0. 05）. There was no serious complication. Conclusion Fiber bronchoscope sputum suction combined with lavage is an active method in the treatment of patients with severe chronic obstructive pulmonary disease.