期刊文献+

特异性免疫治疗在变应性鼻炎合并哮喘治疗中的地位和作用 被引量:4

下载PDF
导出
摘要 近年来随着对特异性免疫治疗作用机制的了解、安全性的认知、有效性的肯定以及询证医学的佐证,对其在整个疾病发病过程中的重要作用有了进一步的认识。1997年世界卫生组织依据特异性免疫治疗机制和临床疗效提出新的术语即特异性变态反应疫苗治疗:指在临床上确诊为变应性鼻炎、变应性哮喘的患者在明确过敏原后,而争对该患者已确定过敏的变应原,配制成变应原提取液并配成各种不同浓度的制剂,由小剂量开始逐渐增加剂量、浓度由低到高反复注射或通过鼻腔、舌下含服等其他给药途径使患者反复接触该种变应原,从而提高机体的耐受性,当患者再次接触此种变应原时,而不再产生过敏现象或过敏现象得以减轻,以达到治疗效果[3]。
出处 《临床肺科杂志》 2013年第4期723-724,共2页 Journal of Clinical Pulmonary Medicine
  • 相关文献

参考文献15

  • 1Noon l.Prophylactic inoculatiot against hay fever[J].Int Arch Allergy Appl Immunol,1953,4:285-288.
  • 2刘虹,洪苏玲.变应性鼻炎的特异性免疫治疗[J].临床耳鼻咽喉头颈外科杂志,2009,23(5):233-236. 被引量:11
  • 3郭永康,徐红.变应性鼻炎特异性免疫治疗的新进展[J].实用临床医学(江西),2009,10(10):135-138. 被引量:2
  • 4孟庆翔,李添应.特异性免疫治疗在变应性鼻炎中的研究[J].国际耳鼻咽喉头颈外科杂志,2006,30(2):87-90. 被引量:10
  • 5Bousquet J,Khaltaev N,Cruza A,et al.Allergic rhintis and its impact on asthma(ARIA) 2008 upda-te(in collaboration with the World Health organization,GA (2) Led and Allergen)[J].Allergy,2008,63 suppl 86:8-160.
  • 6Brozek JL,Baena-Cagnanic E,Bonini S,et al.Methodology for development of the Allergic R-hinitis and its Impct on Asthma guideline 2008 update[J].Allergy,2008,63:38-46.
  • 7Gabrielesson S,Solderlund A,Paulie S,et al.specific Immunotherapy prevents Increased lev-els of Allergen-Specefec IL-4 and Ⅱ-13 producing Cells during Pollen Season[J].Allergy,2001,56(4):293-300.
  • 8Durham SR.Allergen Immunotherapy for Allergic Diseases[J].clin Med,2006,6(4):348-351.
  • 9Bousquet J,Lockey R,Malling H,et al.Allergen Immunotherapy therapeutic vaccines for al-lergic diseases.World Health Organization.American academy of Allergy,Asthma and Immunolo-gy[J].Ann Allergy Athma Immunol,1998,81(5pt1):401-405.
  • 10顾瑞金,主编.变态反应学[M].协和医科大学出版社,2000:369.

二级参考文献70

  • 1开月梅.变应性鼻炎(特异性)免疫治疗患者的依从性及相关因素调查[J].中国中西医结合耳鼻咽喉科杂志,2006,14(3):145-147. 被引量:11
  • 2NOON L. Prophylactic inoculation against hay fever [J]. Int Arch Allergy Appl Immunol, 1953,4:285-288.
  • 3VAN CAUWENBERGE P, BACHERT C, PASSALACQUA G, et al. Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology[J]. Allergy, 2000, 55:116-134.
  • 4BOUSQUET J, VAN CAUWENBERGE P, KHALTAEV N. Allergic and its impact on asthma[J]. J Allergy Clin Immunol, 2001, 108 (5 Suppl) : S147 - 334.
  • 5BOUSQUET J, KHALTAEV N, CRUZ A A, et al. Allergic rhinitis and its impact on Asthma(ARIA) 2008 update (in collaboration with the World Health Organization,GA(2)LEN and AllerGen) [J]. Allergy,2008, 63 Suppl 86:8-160.
  • 6BROZEK J L, BAENA-CAGNANI C E, BONINI S, et al. Methodology for development of the Allergic Rhinitis and its Impact on Asthma guideline 2008 update[J]. Allergy, 2008,63 : 38 - 46.
  • 7WANG Y, BAI C,LI K, et al. Role of airway epithelial cells in development of asthma and allergic rhinitis [J]. Respir Med, 2008,102:949-955.
  • 8KLIMEK L,WOLF H, MEWES T, et al. The effect of short-term immunotherapy with molecular standardized grass and rye allergens on eosinophil cationic protein and tryptase in nasal secretons [J]. J Allergy Clin Immunol,1999,103:47-53.
  • 9WLILSON D R, NOURI-ARIA K T, WALKER S M, et al. Grass pollen immunotherapy: symptomatic improvenment correlates with reductions in eosiophils and IL-5 mRNA expression in the nasal mucosa during the pollen season [J]. J Allergy Clin Immunol, 2001,107:971-976.
  • 10VERHAGEN J,BLASER K,AKDIS C A,et al. Mechanisms of allergen-specific munotherapy: T-regulatory cells and more[J]. Immunol Allergy Clin North Am, 2006,26:207-231.

共引文献22

同被引文献45

引证文献4

二级引证文献79

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部