三七止血胶囊的质量标准研究

A research of the quality standards of panax notoginseng capsule

目的初步建立三七止血胶囊的质量标准。方法用薄层色谱法(thin layer chromatograhy,TLC)对胶囊内容物中的三七作定性鉴别;用高效液相色谱法(high performance liquid chromatography,HPLC)对三七止血胶囊中三七皂苷R1及人参皂苷Rg1、Rb1作定量分析。结果三七皂苷R1及人参皂苷Rg1、Rb1平均回收率分别为94.43%、97.40%、100.61%,RSD为0.95%、0.97%、0.99%。结论本研究所建立之方法可有效地控制三七止血胶囊的质量。

Objective Our research attempted to establish the quality standards for panax notoginseng capsules. Method The capsule content of Panax notoginseng was qualitatively identified with the method of TLC （thin layer chromatography）. The contents of panax notoginseng saponin R1 and ginsenoside Rg1 , Rb1 were determined with the method of HPLC （ high performance liquid chromatography）. Findings The average recovery rate of panax notoginseng saponin R1 and ginsenoside Rg1 , Rb1 was 94.43% , 97.40% , and 100.61%. The RSD was 0.95% , 0.97% , and 0.99%. Conclusion The established methods can effectively control the quality of panax notoginseng capsule.