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人类精子冷冻损伤及保护的研究进展 被引量：13

Human sperm cryopreservation and protection: An update
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摘要 精子的冷冻保存已广泛应用于人类辅助生殖技术,然而,精子在超低温状态下会经历结构、功能的损伤,这种损伤是否会影响到辅助生殖技术的成功率,目前仍然没有一致的共识,世界各地的研究机构一直在致力于精子损伤机制的研究以及冷冻保护的探索,本文就精子冷冻损伤的不同类型以及功能的改变机制进行探讨,结合当前保护研究的最新进展作一综述。 Human sperm cryopreservation has been widely applied in human assisted reproduction technologies, but ultra-low temperature may damage the structure and function of sperm, which in turn may affect the success rate of human reproductive technology. However, this view is not yet universally accepted. Researchers around the world are endeavoring for the mechanisms of cyrodamage and discoveries of cryo-protection. This article gives an overview on the types of human sperm cryodamage, mechanisms of sperm functional changes, and latest discoveries of cryo-protection. Natl J Androi, 2013, 19 （3） ： 262 -265
作者 王尚乾 王巍 张炜
机构地区 南京医科大学第一附属医院泌尿外科
出处 《中华男科学杂志》 CAS CSCD 2013年第3期262-265,共4页 National Journal of Andrology
关键词 人类精子 冷冻保存 冷冻损伤 保护 human sperm cryopreservation cryodamage protection
分类号 R321.1 [医药卫生—人体解剖和组织胚胎学]
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参考文献31

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  • 2Schuffiier A, Morshedi M, Oehninger S. Cryopres^yation of frac-tionated, hi^ily motile human spermatozoa ; Effect on membranephosphatidylserine extemalization and lipid peroxidation. HumReprod, 2001, 16(10): 2148-2153.
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二级参考文献37

  • 1刘睿智,孙妍,许宗革,刘嫒,江露.速冻和缓慢冷冻法对精子运动特征的影响[J].中国男科学杂志,2006,20(1):8-10. 被引量：4
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共引文献27

同被引文献79

引证文献13

二级引证文献45

中华男科学杂志
2013年 第3期

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