中西医结合治疗溃疡性结肠炎临床研究

Clinical Study on Treating Ulcerative Colitis with Integrated Traditional Chinese and Western Medicine

目的:观察中西医结合治疗溃疡性结肠炎的临床疗效。方法:将120例患者随机分为治疗组60例和对照组60例。对照组口服5-氨基水杨酸,1 g,每日4次;治疗组在对照组的基础上加用中药治疗,治法以化瘀行气、清热解毒为主(药物组成:黄连3 g,黄芩、白芍、木香、赤芍、牡丹皮、栀子各10 g,生薏苡仁、红藤、败酱草各30 g,地榆、仙鹤草、槐花各12 g,生甘草5 g)。结果:治疗后,两组主要症状积分及肠镜检查结果积分与治疗前、与对照组治疗后比较,差异均有统计学意义(P<0.05)。对照组有效率为61.67%,治疗组有效率为93.33%,两组有效率比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗溃疡性结肠炎疗效显著。

Objective：To observe the clinical curative effect combination of Chinese traditional and westen medicine treatment of ulcerative colitis. Methods： 120 cases patients were randomly divided into the treatment group and control group, treatment group patients were given 5-anminosalicylic acid per gram, four times a day, the treatment group werre treated with traditional chinese medicine on the basis of control group, treatment with removing blood stasis and promoting blood clearing away heat and toxic material（ the drug composition： huanglian 3 g,huangqin 10 g,baishao 10 g,muxiang 10 g,chishao 10 g,mudanpi 10 g,zhizi 10 g,shengyiyiren 30 g,hongteng 30 g,baijiangcao 30 g,diyu 12 g,xianhecao 12 g,huaihua 12 g,shengganeao 5 g）. Results：After treatment,two group of main symptoms and Enteroseopic examination score before treatment, compared with the control group after treatment, there were statistically significant differenees. The total effective rate was 61.67% in the control and 93.33% in the treatment, difference has patency statistically significant difference （P 〈 0.05 ）in two groups. Conclusion：Traditional Chinese and westen medicine treatment ulcerative colitis has definite effect.