活络散结汤治疗痰瘀互结证渗出性年龄相关性黄斑变性临床研究

Clinical Study of Huoluo Sanjie Decoction in the Treatment of Phlegm and Blood Stasis in Exudative Age-related Macular Degeneration on Each Node

目的:观察活络散结汤治疗痰瘀互结证渗出性年龄相关性黄斑变性的临床疗效。方法:将52例(60眼)患者随机分为治疗组26例(30眼)和对照组26例(30眼)。治疗组予以活络散结汤(方药组成:桃仁12 g,红花12 g,水蛭15 g,茺蔚子12 g,茯苓15 g,半夏12 g,陈皮12 g,三棱6 g,莪术6 g,防风12 g,三七3 g)治疗;对照组口服维生素E、维生素C及葡萄糖酸锌片治疗。结果:在症状疗效方面:对照组有效率为46.2%,治疗组有效率为70.0%,两组有效率比较有显著性差异(P<0.05);在视力疗效方面:对照组有效率为43.33%,治疗组有效率为76.67%,两组比较有显著性差异(P<0.05)。结论:活络散结汤治疗痰瘀互结证渗出性年龄相关性黄斑变性疗效显著,能有效提高患者视力。

Objective：To observe the clinical effect of huoluo Sanjie Decoction in the treatment of active phlegm and blood stasis of exu- dative age-related macular degeneration. Methods ：52 cases（ 60 eyes） were randomly divided into the treatment group of 26 eases（ 30 eyes） and a control group of 26 cases（ 30 eyes）. The treatment group was given huoluo Sanjie Decx^tion （peach 12 g, safflower 12 g, leech 15 g,Fructus Leonuri 12 g,Poria 15 g,12 g of the tuber of pinellia,dried orange peel 12 g,Sparganium 6 g,Curcuma 6 g,wind 12 g,three seven 3 g） treatment ;the control group oral vitamin E,vitamin C, zinc gluconate tablets. Results：In the clinical symptoms：the control group was 46.2%, the effective rate of treatment group was 70.0%, the efficiency of two groups had significant difference （P 〈 0. 05） ;in the visual effects：the control group was 43.33% ,the effective rate of treatment group was 76.67% ,the two groups,there were significant differences （P 〈 0.05 ）. Conclusion： Huoluo Sanjie Deeoction in the treatment of phlegm and blood stasis of exudative age-related macular degeneration, obvious curative effect, can effectively improve the visual acuity.