肾移植前免疫诱导治疗的进展

Progression of induction therapy before kidney transplantation

为晚期肾病患者实施肾移植手术已成为尿毒症患者的最佳治疗方案,可手术后的排异反应始终困扰着医生和患者。术后使用免疫抑制剂是肾移植的常规治疗方案,但人们发现围手术期使用免疫抑制剂进行免疫诱导可降低排异反应的发生,减少术后免疫抑制剂的使用剂量,正逐步成为肾移植免疫学的研究热点。本文为此作一综述。

Renal transplantation has became the best treatment protocols for the end-stage renal disease pations. But the rejection always puzzles doctors and pations after the operations. Immunosuppression is the conventional therapy after transplantation, but many research discovery induction therapy before operation can decrease rejection and dose of immunosuppressive agent. So induction therapy now is becoming warm spot of kidney transplantation immunity.