单烷基乙二胺稀水溶液头基相互作用自组装形成双分子膜

Bilayer Membranes Formed by Monoalkylethylenediamine in Dilute Aqueous Solution through Headgroup Interactions

提出普通表面活性剂(单链两亲分子)亲水头基相互作用诱导疏水尾链平行聚集形成双分子膜的新机制.设计和合成了系列单烷基取代乙二胺C_nH_(2n+1)NHC_2H_4NH_2(n=8,12,14,16,18).通过电镜形态,分散液凝胶/液晶相变和对应铸膜的二维双层结构,表明单链两亲分子头基相互作用和脂链引入刚性片断一样,两者形成的双分子膜具有类似的结构和性能;展示了各体系取代乙二胺双层结构和性能的密切联系.指出了广泛认同的单链两亲分子形成双分子膜必须引入刚性片断的单一成膜机制的片面性,为组装新一类功能头基表面活性剂双分子膜独辟蹊径.

A new idea, enhancing interaction between headgroups to induce the tail - chain parallel orientational arrangement to construct synthetic bilayer membrane, was proposed in this paper. A series of monoalkylethylenediamine, CnH2n + 1 NHC2H4NH2 ( n = 8, 12, 14, 16, 18), was designed and synthesized successfully, and stable bilayer membranes can be formed in various dilute aqueous media. The novel features of the membrane system have been investigated via transmission electron microscope (TEM), differential scanning calorimetry (DSC) and X-ray diffraction (XRD) , and the bilayer packing fashions were conclusively proposed. These results indicate that the importance of the headgroup interaction for the formation of bilayer is the same as that the introduction of a rigid segment, and exhibit the structure - function relationship of the membrane system, which may make possible for the molecular design of novel bilayer membrane by interactions between functional headgroups.