单次经皮冠状动脉介入治疗术前后甲状腺功能及自身抗体无显著变化

No significant effect of iodinated contrast after single percutaneous coronary intervention on thyroid functionand auto-antibodies

探讨单次经皮冠状动脉介入治疗（PCI）术前后甲状腺功能及自身抗体的变化。随机入选PCI患者96例，术前、术后3～6个月测定TSH、T3、T4、甲状腺过氧化物酶抗体（TPOAb）、甲状腺球蛋白抗体（TgAb）并比较。与术前比，术后TSH、T3、T4、TgAb、TPOAb阳性率差异无统计学意义（P〉0．05）。TgAb、TPOAb阳性患者术后TgAb、TPOAb增高（P〈0．05）。单次PCI术碘造影剂短期内对甲状腺功能及自身抗体无显著影响。

The effect of iodinated contrast on thyroid function and auto-antibodies after a single percutaneous coronary intervention （PCI） was explored. In 96 patients with randomly selected PCI, serum TSH, T3 , T4 , thyroid peroxidase antibody （ TPOAb ）, thyroglobulin antibody （TgAb） were determined preoperatively as well as by 3-6 months postoperatively. After PCI, the level of TSH, T3, T4, showed no significant changes; TgAb, TPOAb which were positive preoperatively, after 3-6 months were statistically increased（ P〈0.05 ）. lodinated contrast in PCI has no significant influence on thyroid function and auto-antibodies after 3-6 months.