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自身免疫性淋巴增殖综合征的研究进展 被引量：3

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摘要 自身免疫性淋巴增殖综合征（ALPS）是淋巴细胞凋亡障碍导致淋巴细胞过度聚集并引起淋巴组织增生或自身免疫现象的一组综合征。现将其临床分型、预后、诊治进展等进行综述。
作者 金玲娟(综述) 陈海飞 吴天勤(审校)
机构地区 解放军 苏州大学附属第一医院江苏省血液研究所卫生部重点实验室
出处 《国际输血及血液学杂志》 CAS 2013年第2期110-115,共6页 International Journal of Blood Transfusion and Hematology
关键词 自身免疫 淋巴增殖 诊断 治疗
分类号 R593.2 [医药卫生—内科学]
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参考文献17

  • 1Canale VC, Smith CH. Chronic lymphadenopathy simulating malignant lymphoma. J Pediatr, 1967,70(6) :891-899.
  • 2Sneller MC, Straus SE, Jaffe ES, et al. A novel lyrnphoproliferative/ autoimmune syndrome resembling murine lpr/gld disease. J Clin Invest,1992,90(2):334-341.
  • 3Watanabe-Fukunaga R, Brannan CI, Copeland NG, et al. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature, 1992,356(6367):314- 317.
  • 4Worth A, Thrasher AJ, Gaspar HB. Autoirnmune lymphoproliferative syndrome: molecular basis of disease and clinical phenotype. Br J Haematol, 2006,133 (2) : 124-140.
  • 5Teaehey DT, Seif AE, Grupp SA, et al. Advances in themanagement and understanding of autoimmune lymphopro- liferative syndrome(ALPS). Br J Haematol, 2010,148(2) :205- 216.
  • 6Rieux-Laucat F,Le Deist F, Hivroz C, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science, 1995,268(5215) :1347-1349.
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  • 8Oliveira JB, Bleesing JJ, Dianzani U, et al. Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop. Blood, 2010, 116(14) :e35-e40.
  • 9Rao VK, Oliveira JB. How I treat autoimmune lymphoproliferative syndrome. Blood, 2011 118(22) : 5741-5751.
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同被引文献43

  • 1徐佳,侯桂华.移植免疫耐受中调节性T细胞的研究进展[J].国际免疫学杂志,2007,30(6):393-398. 被引量：5
  • 2Rao VK,Oliveira JB.How I treat autoimmune lymphoproliferative syndrome[J].Blood,2011,118 (22):5741-5751.
  • 3Teachey DT.New Advances in the Diagnosis and Treatment of Autoimmune Lymphoproliferative Syndrome (ALPS)[J].Curr Opin Pediatr,2012,24(1):1-8.
  • 4Lenardo MJ,Oliveira JB,Zheng L,et al.ALPS-Ten Lessons from an International Workshop on a Genetic Disease of Apoptosis[J].Immunity,2010,32(3):291-295.
  • 5Strasser A,Jost PJ,Nagata S.The many roles of FAS receptor signaling in the immune system[J].Immunity,2009,30(2):180-192.
  • 6Caminha I,Fleisher TA,Hornung RL,et al.Using biomarkers to predict the presence of FAS mutations in patients with features of the autoimmune lymphoproliferative syndrome[J].J Allergy Clin Immunol,2010,125 (4):946-949.
  • 7Wang X,Haroon F,Karray S,et al.Astrocytic Fas ligand expression is required to induce T-cell apoptosis and recovery from experimental autoimmune encephalomyelitis[J].Eur J Immunol,2013,43(1):115-124.
  • 8Magerus-Chatinet A,Stolzenberg MC,Lanzarotti N,et al.Autoimmune lymphoproliferative syndrome caused by a homozygous null FAS ligand (FASLG) mutation[J].J Allergy Clin Immunol,2013,131 (2):486-490.
  • 9Ramaswamy M,Cleland Y,Cruz AC,et al.Many checkpoints on the road to cell death:regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses[J].Results Probl Cell Differ,2009,49:17-47.
  • 10Wu J,Richards MH,Huang J,et al.Human FasL gene is a Target of β-Catenin/T-Cell factor pathway and complex FasL haplotypes alter promoter functions[J].PLoS ONE,2011,6(10):e26143.

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国际输血及血液学杂志
2013年 第2期

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