脾氨肽对不同水平IgG的反复呼吸道感染患儿疗效分析

Therapeutic efficacy on RRI in different of IgG with spleen aminopeptide oarl lyophilized powder

目的:研究使用脾氨肽对不同水平IgG的反复呼吸道感染患儿的治疗效果,为临床治疗反复呼吸道感染提供参考依据。方法:对确诊为反复呼吸道感染的1～3岁的100例患儿,分别测定IgG水平,应用脾氨肽治疗1个月与3个月、1年分别对患儿进行随访调查了解治疗效果,分析对比不同IgG水平与反复呼吸道感染的疗效。结果:经统计分析,IgG水平在8.0～10.09 g/L正常组2使用脾氨肽治疗3个月时有效率最高,达到87.5%;1个月时经检验正常1组、正常2组、异常组有效率对比,差异均无统计学意义(P>0.05);3个月时,正常2组与正常1组及异常组的有效率比较,差异有统计学意义(P<0.05);1年时,正常2组有效率明显高于异常组,差异有统计学意义(P<0.05)。结论:脾氨肽对IgG正常或异常水平的反复呼吸道感染患儿均有改善,以IgG水平在8.0～10.09 g/L的患儿的治疗效果最好。

Objective Research the treatment effect of the RRI on different level of IgG with spleen aminopeptide oarl lyophilized powder, to provide the reference for clinical.Methods The 1 - 3 years old 100 cases RRI children who were diagnosed of were derermined the IgG level,application of the spleen aminopeptide oarl lyophilized powder after one month, three months and one year, follow-up with investigating treatment effect,analyze the relationship with different level of IgG and curative effect.Results The statistical analysis,the effective rates which the IgG level of 8.0 - 10.09 g/L was the highest after using of spleen aminopeptide oarl lyophilized powder to treat the RRI three months later, achieve 87.5%.in the one month,three groups of efficient were not statistically significant（P 〉 0.05）;in the three months,compared with 1 group of normal and abnormal group,the effective rates of the 2 group of normal were statistically significant（P 〈 0.05）.one year later,the effective rate in the 2 group was higher than the abnormal group,and they have the statistically significant（P 〈 0.05）.Conclusion Spleen aminopeptide oarl lyophilized powder can improve the effective rate in RRI children,whether normal or abnormal levels of IgG,and the best treatment of effective rate was the IgG in 5.09 ～8 g/L.