期刊文献+

基质金属蛋白酶抑制剂研究进展 被引量:5

下载PDF
导出
摘要 基质金属蛋白酶可降解细胞外基质及基底膜 ,在肿瘤局部侵袭及转移过程中起关键性作用 ,以其作为治疗靶点可有效控制肿瘤的生长及转移。目前已开发并发现数种基质金属蛋白酶抑制剂 ,正处于临床前及临床试验阶段。本文综述该领域的最新研究进展。
作者 张苏江 姜藻
机构地区 南京铁道医学院
出处 《国外医学(肿瘤学分册)》 北大核心 2000年第5期283-285,共3页 Foreign Medical Sciences (Cancer Section)
  • 相关文献

参考文献1

二级参考文献1

共引文献2

同被引文献44

  • 1韩明权,刘嘉湘,高虹,朱晏伟,陈善香.24味中药对人肺腺癌细胞核酸和蛋白质及细胞周期的影响观察[J].中国中西医结合杂志,1995,15(3):147-149. 被引量:66
  • 2Hiroshi Sato,Yuri Kida,Masayoshi Mai,et al.Expression of genes encoding type Ⅳ collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells[J].Oncogen,1992,7:77-83.
  • 3Ornstein DL,Macnab J Cohn KH.Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer[J].Clin Exp Metastasis,1999,17(3):205-212.
  • 4Grigioni WF,D'Errico A,Fortunato C,et al.Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane[J].Mod Pathol,1994,7(2):220-225.
  • 5Pajouh MS,Nagle Rb,Breathnach R,et al.Expression of metalloproteinase genes in human prostate cancer[J].J Cancer Res Clin Oncol,1991,117:144-150.
  • 6McDonnell S.Navre M,Coffey RJ Jr,et al.Overexpression and localization of the matrix metalloproteinase pump-1(MMP-7) in human gastric and colon carcinama[J].Mol Carcinogen,1991,4(6):527-533.
  • 7Garbett EA, Reed MW, Brown NJ, et al. Proteolysis in human breast and colorectal cancer[J]. Br J Cancer, 1999, 81(2) :287-293
  • 8Davies B, Waxman J, Wasan H, et al. Levels of Matrix metalloproteinases in bladder cancer correlate with tumor grade and invasion[J]. Cancer Res, 1993,53(22) :5 365-5 369
  • 9Monteagudo C, Merino MJ, San JJ, et al. Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue[J]. J Pathol, 1990,136(3):585-592
  • 10Levy AT, Cioce V, Sobel ME, et al. Increased expression of the Mr 72000 type IV collagenase in human colonic adenocarcinoma[J]. Cancer Res, 1991,51(1):439-444

引证文献5

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部