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乳腺癌内分泌治疗的耐药与对策 被引量:4

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摘要 乳腺癌对内分泌治疗耐药是影响乳腺癌治疗效果和预后的重要因素。近几年对乳腺癌内分泌治疗耐药机制研究有较大进展 ,并研究出了一系列新的抗雌激素药物和新的芳香化酶抑制剂 ,特别是非选择性雌激素受体抑制剂法洛德西 (faslodex)以及新的芳香化酶抑制剂瑞宁得 (arimidex ,anastrozole)、来曲唑 (letrozole,femara)和福美司坦 (formestane)等对三苯氧胺或氨鲁米特耐药乳腺癌显示一定疗效 ,现正在做进一步临床观察并研究更好的用药方案。
出处 《国外医学(肿瘤学分册)》 北大核心 2000年第5期303-306,共4页 Foreign Medical Sciences (Cancer Section)
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  • 1Winrich Rauschning,Kathleen I. Pritchard. Droloxifene, a new antiestrogen: Its role in metastatic breast cancer[J] 1994,Breast Cancer Research and Treatment(1):83~94

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  • 1王佳玉,徐兵河.芳香化酶抑制剂在乳腺癌内分泌治疗中的地位及展望[J].中华肿瘤杂志,2004,26(8):507-508. 被引量:13
  • 2王甜甜,马榕.乳腺癌内分泌治疗研究现状[J].中国现代普通外科进展,2004,7(5):260-262. 被引量:13
  • 3RoseC. A comparison of the efficacy of aromatase inhib- itors in secondlinet reatment of metastatic breast cancer [J]. Am J Olin Oncol,2003, 26 (4) : S9-S16.
  • 4Bonneterrre J,Thurlimann B, Robertson JF, et al. Anas- trozole versus tamoxifen as first - line therapy for advan- cel breast cancer in 668 postmenopausal women:results of the Tamoxifen Randomized Group Efficacy and Toler- ability study [ J ]. J Clin Oncol, 2000, 18 ( 22 ) : 3748- 3757.
  • 5Mouridsen H, Gershanovich M, Sun Y, et al. Phase 3 study of letrozole versus tamoxifen as first - line therapy of advanced breast cancer in postmenopausal wonmen: analysis of survival and update of efficacy from the in- ternational letrozole Breast Cancer Group [ J ]. J Clin Oncol,2003,21 ( 11 ) :2101-2109.
  • 6Paridaens R, Therasse P, Dirix L, et al. First Line hor- monal treastment (HT) for metastatic breast cancer ( MBC ) with exemestane ( E ) or tamoxifen (T) in postm- enopausal patients (pts) - a randomized phase 3 trial of the EORTC breast group[ J]. Proc Am Soc Clin Oncol, 2004,23 : 6.
  • 7Uramoto H, Kagami S, Lwashige A, et al. Hormone therapy for beast cancer [ J ]. JUOEH, 2006,28 ( 3 ) : 287 -294.
  • 8Kelleher M, Miles D. The adjuvant treatment of breast cancer[J]. Int JClin Pract,2003,57 (3) :195-199.
  • 9Krainick Strobel UE, LichteneggerW, Wallwiener D, et al. Neoadjuvant letrozole in postmenopausal estrogen and/or progesterone receptor positive breast cancer: a phase IIb/III trial to investigate optimal duration of pre- operative endocrine therapy[J]. BMC Cancer,2008, 26 (8) : 62.
  • 10Gil MJ Barnadas A, Cireral L, et al. Primary hormonal therapy with exemestane in patients with breast tumors > 3 em in diameter: results of a Spanish multicenter phase 2 trial [ J ]. Proe Am Soe Clin Oncol, 2004,23 : 27.

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