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经鼻间歇正压通气与经鼻持续气道正压通气治疗新生儿呼吸窘迫综合征疗效分析 被引量:43

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摘要 目的比较经鼻间歇正压通气(NIPPV)与经鼻持续气道正压通气(NCPAP)在新生儿呼吸窘迫综合征(RDS)中的疗效。方法选择本院新生儿重症监护病房2010年6月至2012年7月收治的RDS患儿,随机分为NIPPV组和NCPAP组,比较两组治疗成功率、血气变化、应用NIPPV和NCPAP时间、并发症、两组治疗后需气管插管机械通气的比例及预后。结果两组患儿基本情况和RDS分级差异无统计学意义(P均>0.05)。NIPPV组(48例)治疗成功44例(91.7%),NCPAP组(50例)治疗成功38例(76.0%),两组差异有统计学意义(P<0.05)。NIPPV组治疗后1、12h的pH值、PaCO2、PaO2比NCPAP组改善更明显,两组比较差异有统计学意义(P<0.01)。NIPPV组治疗时间短于NCPAP组,NIPPV组需气管插管机械通气的比例低于NCPAP组,差异有统计学意义(P<0.01),部分NCPAP治疗失败病例(5/12)改为NIPPV治疗取得成功。结论 NIPPV治疗RDS疗效优于NCPAP。
出处 《中国新生儿科杂志》 CAS 2013年第2期96-98,共3页 Chinese Journal of Neonatology
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