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明目地黄丸对白内障大鼠晶状体内SOD、MDA影响的实验研究 被引量:3

Effect of Mingmu Dihuang pill on SOD and MDA in lens of cataract rat
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摘要 [目的]研究明目地黄丸对白内障大鼠晶状体中超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量的影响。[方法]建立大鼠白内障模型,采用黄嘌呤氧化酶法和硫代巴比妥酸(TBA)法对模型组、治疗组及对照组大鼠晶状体中SOD活性和MDA含量进行检测。[结果]明目地黄丸高、中剂量组大鼠晶状体中MDA含量明显低于模型组,高、中剂量组大鼠晶状体中SOD活性明显高于模型组,差异具有显著性(P<0.05)。[结论]明目地黄丸能明显降低白内障大鼠晶状体中MDA含量,且能明显升高白内障大鼠晶状体中SOD活性。 [Objective] To observe the effect of Mingmu Dihuang pills on SOD and MDA in lens of cataract rats. [Methods] SOD and MDA in lens of rats with cataract were detected by biochemistry kits. [Results] The levels of MDA in lens of the rats of high and middle dose groups were lower significantly than that of the model group (P〈0.05). The SOD activity of the rats of high and middle dose groups were higher significantly than that of the model group (P〈0.05). [Conclusion] Mingmu Dihuang pills may significantly decrease the MDA and increase the SOD activity in the lens of the cataract rats.
出处 《天津中医药》 CAS 2013年第2期102-104,共3页 Tianjin Journal of Traditional Chinese Medicine
基金 河北省张家口市科学技术和地震局2012年度科学技术研究与发展计划项目(1221042D)
关键词 超氧化物歧化酶 丙二醛 明目地黄丸 白内障 SOD MDA Mingmu Dihuang pill cataract
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