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血浆脑钠肽检测在慢性心力衰竭诊断中的意义 被引量:1

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摘要 目的分析血浆脑钠肽(BNP)检测在慢性心力衰竭诊断中的临床价值。方法选择慢性心力衰竭患者80例,按照美国纽约心脏病学会功能分级(NYHA)分为4组,在治疗前和治疗结束后测定脑钠肽的含量,同时利用超声心动图仪检测左心室舒张末期内径(LVEDD)、左心室射血分数(LVEF),并与健康人进行对比。结果观察组患者BNP水平明显高于健康人,Ⅰ级到Ⅳ级BNP水平逐渐增加,治疗后BNP、LVEDD均较治疗前显著降低,LVEF较治疗前明显增加。结论 BNP可作为诊断CHF的重要指标,可以通过BNP判断心衰的严重程度、左心室舒张功能,同时也可以作为临床治疗效果评价的指标。
出处 《青岛医药卫生》 2013年第1期45-46,共2页 Qingdao Medical Journal
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  • 1王岚峰,吴双,关秀茹,张蕾,沈景霞,薛凤华.脑钠素与急性心肌梗死预后关系的临床研究[J].中华心血管病杂志,2005,33(3):234-237. 被引量:66
  • 2Prontera C, Emdin M, Zucchelli GC, et al. Analytical performance and diagnostic accuracy of a fully automated electrochemiluminescent assay for the N-terminal fragment of the pro-peptide of brain natriuretic peptide in patients with cardiomyopathy: comparison with immunoradiometric assay methods for brain natriuretic peptide and atrial natriuretic peptide. Clin Chem Lab Med ,2004,42:37-44.
  • 3Berendes E, Schmidt C, Van Aken H, et al. A-type and B-type natriuretic peptides in cardiac surgical procedures. Anesth Analg,2004, 98:11-19.
  • 4Mair J, Hammerer-Lereher A, Puschendorf B. The impact of cardiac natriuretic peptide determination on the diagnosis and management of heart failure. Clin Chem Lab Med ,2001,39 :571-588.
  • 5Mueller T, Gegenhuber A, Poelz W, et al. Biochemical diagnosis of impaired left ventricular ejection fraction-comparison of the diagnostic accuracy of brain natriuretic peptide (BNP) and amino terminal proBNP (NT-proBNP). Clin Chem Lab Med, 2004,42:159-163.
  • 6Michael G,Petersen W,Daniel B. Natriuretic peptides in the diagnosis and management of heart failure[J]. CMAJ, 2006,175(6) : 611-617.
  • 7Sadanandan S,Cannon CP,Chekuri K,et al.Association of elevated B-type natriuretic peptide levels with angiographic findings among patients with unstable angina and non-ST-segment elevation myocardial infarction[J].J Am Coll Cardiol,2004,44(3):564-568.
  • 8Kiechl S,Schett G,Wenning G,et al.Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease[J].Circulation,2004,109(18):2175-2180.
  • 9Jono S,IkariY,ShioiA,et al.Serum osteoprotegerin levels are associatedwith the presence and severity of coronary artery disease[J].Circulation,2002,106(10):1192-1194.
  • 10Schoppet M,Sattler AM,Schaefer JR,et al.Increased osteoprotegerin serum levels in men with coronary artery disease[J].J Clin Endocrinol Metab,2003,88(3):1024-1028.

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