重度肥胖对肺功能及运动试验中呼吸模式的影响

The effects of morbidly obesity on pulmonary function and breathing patterns of exercise testing

目的：研究重度肥胖对肺功能及运动试验中呼吸模式的影响。方法：４２名女性受试者，正常体重组２０名，重度肥胖组２２名，进行肺功能及功率车运动试验测定。结果：肥胖组补呼气量、功能残气量、残气量及肺总量均比对照组显著降低（Ｐ＜０．０５）。肥胖组静息状态、无氧阈状态和极量运动状态的氧耗量均比对照组显著增高（Ｐ＜０．０５），而公斤氧耗量均比对照组显著降低（Ｐ＜０．０１）。无氧阈状态和极量运动状态时，肥胖组的分钟通气量、呼吸频率、生理死腔与潮气量的比值以及氧的通气当量均高于对照组，而潮气量均小子对照组，差异有显著性（Ｐ〈０．０５）。结论：重度肥胖可使肺容量减少、运动中的组织供氧能力及胸壁顺应性、肺顺应性下降，呈现浅快呼吸模式。

Objective: To determine the effects of morbidly obesity on pulmonary function and breathing patterns of exercise testing. Methods: Twenty. women with normal weight and 22 with morbidly obesity were included in this study. All patients underwent pulmonary spirometry and ergometer exercise test. Results: Several parameters of lung volume significantly decreased in the obese women (P<0.05). Oxygen consumption expressed in mL/min was significantly higher (P<0.05), but it was significantly lower when expressed in mL/kg. min) in obese women during exercise (p<0.0l). Minute ventilation, respiratory rate, the ratio of physiological dead space to tidal volume and oxygen ventilation equivalence were significantly higher while tidal volume was significantly lower in obese patients at AT and maximal exercise (P<0.05). ConcluSion: Lung volumes, the ability of oxygen uptake and chest wall and lung compliance decrease with rapid and shallow breathing Patterns in morbidly obese individuals during exercise.