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分析血清半胱氨酸蛋白酶抑制剂C在肾移植术后肾功能监测中的应用价值

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摘要 目的分析血清半胱氨酸蛋白酶抑制剂C(Cys C)在肾移植术后肾功能监测中的应用价值。方法选取同种异体肾移植患者24例(研究组)和健康体检者20例(对照组)。所有患者于术前和术后空腹采集静脉血,检测其血清Cys C、尿素(Urea)、肌酐(Scr)和尿酸(UA)的浓度。比较两组相关参数的差异。结果术前1d和术后1d血清Cys C浓度显著高于对照组(P<0.05);术前1d和术后1、3d血清Scr浓度显著高于对照组(P<0.05);术前1d和术后1、3、7、14、21、28d血清Urea浓度显著高于对照组(P<0.05)。Cys C判断肾功能受损的准确性、敏感性和特异性分别为71.6%、82.5%和64.8%,均高于Scr和Urea。结论 Cys C可作为肾移植术后监测肾功能较理想的血清标志物。
出处 《中国卫生产业》 2013年第4期87-87,175,共2页 China Health Industry
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