高频彩超在颈动脉粥样硬化斑块与脑梗死相关性研究中的价值

High Frequency Color Doppler Ultrasound in Carotid Atherosclerotic Plaque and Cerebral Infarction in the Study of Value Relevance

目的探讨高频彩超在颈动脉粥样硬化斑块与脑梗死相关性研究中的价值。方法对110例经CT、MRI检查确诊的脑梗死患者及110例相应年龄的健康体检者作为对照组进行双侧颈动脉彩色多普勒超声检查,观察斑块的发生部位及性质,血流充盈缺损及管腔狭窄及闭塞程度。结果脑梗死患者中,颈动脉粥样斑块形成102例(92.72%),对照组中颈动脉粥样斑块形成18例(16.36%),差异具有统计学意义(P<0.05);脑梗死组中软斑、混合斑的检出率明显高于对照组,两组对照差异具有统计学意义(P<0.05);梗死组颈动脉狭窄发生率明显高于对照组,且脑梗死组颈动脉中、重度狭窄明显多于对照组,两组对照差异具有统计学意义(P<0.05);两组斑块均多见于颈总动脉分叉处,其次为颈内动脉起始部及颈总动脉主干,两组对照差异无统计学意义(P>0.05)。结论颈动脉粥样硬化斑块与脑梗死有密切的相关性,尤其是颈动脉粥样硬化斑块中的软斑、混合斑是造成脑梗死的重要原因;高频彩色多普勒超声在颈动脉粥样硬化斑块与脑梗死的关系研究中具有重要作用。

Objetive To investigate the high frequency color Doppler ultrasound in carotid atherosclerotic plaque and cerebral infarction in the study of value relevance. Methods 110 patients with CT diagnosed by MRI, the group of cerebral infarction patients and 110 cases of corresponding age healthy subjects as control group were bilateral carotid artery with color Doppler ultrasound examination, observation of plaque location and nature, blood filling defect and luminal stenosis and occlusion of degree. Results In the patients with cerebral infarction, carotid atherosclerotic plaque formation in 102 cases （92.72%）, a control group of 18 cases of carotid artery atherosclerotic plaque formation （16.36%）, the difference was statistically significant （P 〈 0.05） ; cerebral infarction group soft spot, mixed plaque detection rates were significantly higher than that of the control group, the two group difference has statistics significance （P 〈 0.05） ; the incidence of carotid stenosis cerebral infarction group was higher than that of control group, and the group of cerebral infarction carotid artery severe stenosis, significantly more than the control group, the two group difference has statistics significance （P 〈 0.05） ; two groups of plaques were found in the carotid artery bifurcation, followed by internal carotid arteries and carotid artery trunk, two groups had no significant difference （P 〉 0.05）. Conclusion The carotid atherosclerotic plaque and cerebral infarction have a close correlation between carotid atherosclerotic plaques, especially in soft spot, mixed stain is the main reason causing brain infarction; high frequency color Doppler ultrasound in carotid atherosclerotic plaque and cerebral infarction study plays an important role in.