中药综合治疗对糖尿病足早期周围神经病变神经传导速度的影响

Influence of the traditional Chinese medicine therapy on the nerve conduction velocity of early diabetic foot

目的观察中药综合治疗对糖尿病足早期周围神经病变神经传导速度的影响。方法选择62例糖尿病足初期合并周围神经病变患者,随机分为治疗组与对照组,给予糖尿病基础治疗的同时,治疗组采用中药内服加外洗,对照组口服甲钴胺,4周为1个疗程,治疗2个疗程。观察治疗前后两组临床症状、肌电图神经传导速度的变化情况。结果两组临床症状均明显改善,治疗组的总有效率明显高于对照组(P<0.01),肌电图神经传导速度改善明显优于对照组(P<0.01)。结论中药综合治疗糖尿病足早期周围神经病变有较好疗效,且无不良反应。

Objective To observe the traditional Chinese medicine therapy for treatment of early diabetic foot clinic effect of peripheral nerve lesions, and to explore its mechanism of action. Methods 62 elderly patients with diabetic foot （early） peripheral neuropathy were randomly divided into two groups. 32 cases in the treatment group were treated with the internal and external administration of the Chinese herbs ; 30 cases in the control group received basic treatment of taking o- rally methylcobalamin. We took 4 weeks as a course of treatment, and the changes of clinical symptoms and electromyogra- phy of nerve conduction velocity of two groups were observed before and after treatment of 8 weeks. Results The total ef- fective rate in the treatment group was significantly higher than that in the control group （P 〈 0.05）. Two groups of motor nerve conduction （MNCV） and sensory nerve conduction （SNCV） were improved （P 〈 0.01 ）, but the treatment group was better than control group （P 〈 0.01 ）. Conclusion The combined therapy of TCM can obviously improve the early aged diabetic foot nerve conduction velocity of peripheral nerve lesions.