心理干预改善功能性消化不良患者焦虑、抑郁状态的效果观察

Effect Observation of Mental Intervention in Improvement of Anxiety and Depressive State of Patients with Functional Dyspepsia

目的探讨心理干预改善功能性消化不良(functional dyspepsia,FD)患者焦虑、抑郁状态的临床效果。方法选择2007年10月—2008年3月在我院住院并确诊的FD 45例,随机分为观察组(21例)和对照组(24例)。观察组在常规治疗基础上同时实施心理干预,对照组仅进行常规治疗。两组皆于治疗前后采用Zung抑郁自评量表(SDS)、Zung焦虑自评量表(SAS)进行焦虑、抑郁症状评估,健康调查简表(SF-36)综合评价生存质量,并进行比较。结果治疗前两组SDS、SAS和SF-36评分比较差异均无统计学意义(P>0.05)。治疗后两组焦虑、抑郁症状评分均较治疗前显著下降,差异有统计学意义(P<0.05),生存质量各方面评分均较治疗前显著增加,差异亦有统计学意义(P<0.01)。治疗后观察组焦虑、抑郁症状评分均低于对照组,差异有统计学意义(P<0.05);生存质量评分中,RP和RE评分亦均低于对照组,差异亦有统计学意义(P<0.05)。结论对FD患者实施健康教育、认知-行为疗法及音乐疗法3种方法相结合的心理干预,可明显改善焦虑、抑郁状态,并可使生存质量得到一定程度改善。

Objective To explore clinical effect of mental intervention in improvement of anxiety and depressive state of patients with functional dyspepsia （FD）. Methods A total of 45 patients with FD during October 2007 and March 2008 in our hospital were randomly divided into therapy group （n = 21 ） and control group （n = 24）. The therapy group was given mental in- tervention on the basis of conventional therapy, while the control group was only given conventional therapy. The anxiety and de- pressive state of the two groups were evaluated with Zung self-rating depression scale （SDS） and Zung self-rating anxiety scale （SAS） before and after the treatment. The quality of life in two groups were evaluated with SF-36 and were also compared. Re- suits The differences of SDS, SAS and SF-36 were not statistically significant before the treatment （P 〉0.05）. The scores of anxiety and depressive state decreased significantly after the treatment than those before the treatment （P 〈 0.05）, the quality of life scores increased significantly after the treatment than those before the treatment （P 〈 0. O1 ）. The scores of anxiety and de- pressive state in therapy group were significantly lower than those of control group （P 〈 0.05） ; the scores of physiological func- tion and emotional function in therapy group were significantly lower than those of control group （P 〈 0.05）. Conclusion The combination of health education, cognitive behavior therapy and music therapy in treatment of patients with FD can obviously im- prove the anxiety and depressive states, and improve the quality of life to a certain extent.