血液净化治疗急性中毒的应用进展

Application Advances in Blood Purification Treating Acute Poisoning

急性中毒患者体内毒物大量积聚,快速及时地清除体内毒物并减轻毒物对脏器功能的损害是治疗急性中毒的关键。血液净化能够清除体内毒物,并减轻炎性因子对器官功能的损害,是急性中毒的有效治疗手段之一。血液净化方式已经历了血液透析、连续性肾脏替代等的发展历程,功能上也由肾脏替代演变为多器官功能支持以及生命支持,这将为中毒性疾病的治疗带来新的契机。

The acute poisoned patients have abundant poison accumulation,so the key treatment is to remove the toxic timely and alleviate the damage of toxicant on organs.Blood purification can remove the toxic and reduce multiple organ damages of inflammatory factors,thus is an effective treatment for acute poisoning.Blood purification methods have passed the courses of development of hemodialysis,continuous renal replacement therapy and so on,and the function has also developed from renal replacement to multiple organ function support and life support,which will bring a new chance to the treatment of poisoning.