多发性骨折与全身炎症反应综合征

Multiple fracture and systemic inflammatory response syndrome

目的 分析多发性骨折后全身炎症反应综合征 (SIRS)的发生率及发病原因 ,提出预防和治疗原则。方法 多发性骨折 87例 ,分为SIRS组和非SIRS组 ,以比较两组的病死率。又以失血量分组 ,分析SIRS与失血量的关系。结果 多发性骨折SIRS发生率为 5 8 6 % ,病死率为 13 7% (P <0 0 5 )。随失血量增大 ,多发性骨折SIRS发生率升高 (r =1,P <0 0 5 )。结论 多发性骨折的SIRS发生率和病死率较高 ,SIRS的发生与失血量成正相关。

Objective To study incidence and causes of the systemic inflammatory response syndrome after multiple fracture and suggest principles of prevention and treatment. Methods 87 patients were divided into systemic inflammatory response syndrome(SIRS) and non SIRS group. The mortality rate of SIRS were compared with that of non SIRS group. The relationship between SIRS and the effect of loss of blood was observed. Results\ SIRS occurred in 58 6% multiple fracture and mortality rate was 13 7%( P <0 05). When blood loss increased, the morbidity rate of SIRS increased( r =1, P <0 05). Conclusion The morbidity and mortality of SIRS are higher in multiple fracture. The blood loss is positively related with SIRS.