精索静脉曲张青少年精索内静脉病理改变

Pathological Changes of Internal Spermatic Veins of Adolescent Varicocele

目的 :探讨青少年精索静脉曲张的发病机制。 方法 :应用光镜和电镜观察 30例青少年精索静脉曲张病人精索内静脉 (ISV)的病理改变。 结果 :内皮细胞出现大的空泡 ,髓样小体增多 ;严重者内皮细胞缺失 ,平滑肌细胞增生 ,可见双核改变 ,胞质内出现髓样小体 ,肌间有大量的胶原纤维。 结论 :ISV的病理改变和血流障碍之间互为因果 ,相互影响 ,恶性循环 ,可能是精索静脉曲张的主要病理机制。

Objectives: To study the pathological mechanism of adolescent varicocele. Methods: Pathological changes and ultrastructure of ISV taken from 30 adolescent varicoceles were observed by light microscopy and electronic microscopy . Results: Big vacuoles and many marrow like corpuscles appeared in endothelial cells, and some endothelial cells were lost. Smooth muscle cells hyperplasia, binuclear smooth muscle cells and collagen fibers proliferation took place . Conclusions: The structural changes which result from abnormal venous blood circulation may cause development of adolescent varicocele.