摘要
在心外科手术中，心肌保护效果与手术患者的术后恢复和远期预后都有着密切的关系，而心脏停搏液则是提供良好的心肌保护效果的关键。传统的高钾停搏液因其去极化的特点可引起持续性跨膜离子流及能量消耗，导致患者术后心功能不全或心肌顿抑。
出处
《中国体外循环杂志》
2013年第1期61-64,共4页
Chinese Journal of Extracorporeal Circulation
参考文献32
-
1Chambers D J, Fallouh HB. Cardioplegia and cardiac surgery: pharmacological arrest and eardioprotection during global ische- mia and reperfusion [J]. Pharmacol Ther, 2010, 127(1) :41 - 52.
-
2Chambers DJ, Hearse DJ. Developments in eardioprotection: " polarized" arrest as an alternative to "depolarized" arrest [ J ]. Ann Thorac Surg, 1999, 68(5) :1960 -1966.
-
3Peart J'N, Headrick JP. Adenosinergic cardioprotection: multi- ple receptors, multiple pathways [ J]. Pharmacol Ther, 2007, 114(2) :208 -221.
-
4Mantovani V, Mariscalco G, Borsani P, et al. Effects of adeno- sine and defibrotide adjunct to a standard crystalloid cardiople- gie solution [J]. J Cardiovasc Surg (Torino), 2005, 46(3) : 291 - 296.
-
5Jakobsen O, Stenberg TA, Losvik O, et al. Adenosine insteadof supranormal potassium in cardioplegic solution preserves en- dothelium - derived hyperpolarlzation factor - dependent vasodi- lation [J]. Eur J Cardiothorac Surg, 2008, 33(1) :18 -24.
-
6Liu R, Xing J, Miao N, et al. The myocardial protective effect of adenosine as an adjunct to intermittent blood cardioplegia dur- ing open heart surgery [J]. EurJ Cardiothorac Surg, 2009, 36 (6) :1018 - 1023.
-
7Ahlsson A, Sobrosa C, Kaijser L, et al. Adenosine in cold blood cardioplegia - - a placebo - controlled study [ J]. Inter- act Cardiovasc Thorac Surg, 2012, 14( 1 ) :48 -55.
-
8E1 - Menyar A, Gehani A. Adenosine - induced tachyarrhyth- mia and cardiac arrest [J]. Future Cardiol, 2010, 6(4) : 433 -436.
-
9Katayama O, Ledingham SJ, Amrani M, et al. Functional and metabolic effects of adenosine in cardioplegia: role of tempera- ture and concentration [J]. Ann Thorac Surg, 1997, 63(2) : 449 - 454.
-
10He GW, Ge ZD, Yim AP, et al. Electrophysiologic and me- chanical evidence of superiority of hyperpolarizing versus depo- larizing cardioplegia in protection of endothelium - derived hy- perpolarizing factor - mediated endothelial function : a study in coronary resistance arteries [ J ]. J Thorac Cardiovasc Surg, 2004, 127(6): 1773-1780.
二级参考文献11
-
1陈晓东,王志农,张宝仁,朱家麟,蔡凯华,丁芳宝.体外循环中心肌缺血再灌注损伤与恢复的超微结构研究[J].第二军医大学学报,1997,18(S1):82-85. 被引量：17
-
2[3]Martin HB,Walter CL.Preconditioning:an endogenous defense against the insult of myocardial ischemia[J].Anesth Analg,1996,83(3):639-645.
-
3[4]Fliss H,Gattinger D.Apoptosis in ischemic and reperfused rat myocardium[J].Circ Res,1996,79(5):949-956.
-
4[5]Javadov S,Karmazyn M.Mitechondrial permeability transition pore opening as an endpoint to initiate cell death and as putarive target for cardioprotection[J].Cell Physiol Biochem,2007,20(1-4):1-22.
-
5[7]Bevers EM,Comfurius P,Dekkers DW,et al.Regulatory mechanisms of transmembrane phospholipid distributions and pathophysiological implications of transbilayer lipid scrambling[J].Lupus,1998,7(supp12):s126-131.
-
6[8]Richter C.Pro-oxidants and mitochondrial Ca2+:their relationship to apoptosis and oncogenesis[J].FEBS,1993,325(1-2):104-107.
-
7[9]Fabisiak JP,Kagan VE,Ritov VB,et al.Bcl-2 inhibits Betective oxidation and externalization of phosphatidylsefine during paraquat-induced apoptosis[J].Am J Physiol,1997,272(2Pt 1):C675-684.
-
8[10]Freude B,Masters TN,Robicsck F,et al.Apoptoeis is initiated by myocardial ischemia and executed during reperfusion[J].J Mol Cell Cardiol.2000,32:197-208.
-
9[11]Grover GJ,Garlid KD.ATP-Sensitive potassium channels:A review of their cardioprotective pharmacology[J].J Mol Cell Cardiol,2000,32(4):677-695.
-
10曾志勇,王志农,徐志云,王军,何斌,张宝仁.缺血预处理对心肌组织酶的活性影响实验研究[J].中国体外循环杂志,2003,1(3):167-169. 被引量：1
同被引文献2
-
1万秋霞,李德辉,李文志,王楠,周华成,孙承英,包芳萍.大鼠静脉输注罗哌卡因与利多卡因混合液的毒性反应[J].中华麻醉学杂志,2004,24(9):681-684. 被引量：4
-
2于淑侠,马正良,顾小萍,王尔华.利多卡因持续静脉泵注对鼻内窥镜术中异氟醚用量及术后疼痛的影响[J].临床麻醉学杂志,2010,26(6):494-496. 被引量：7
引证文献2
-
1王雷,肖立琼,杨婷,陈鑫.晶体心脏停跳液联合利多卡因在成人单纯二尖瓣置换术中的应用[J].临床药物治疗杂志,2018,16(4):52-54. 被引量：2
-
2黄成锋,朱平,李小辉,郑少忆,卢聪,郭惠明,庄建.离体心脏的心肌保护[J].中华胸心血管外科杂志,2016,32(1). 被引量：1
二级引证文献3
-
1李斯林,孙煦勇,秦科,李海滨,莫安胜,侯善升,莫仁才,刘军,黎艳培,黄燕嫣.巴马小型猪心脏移植模型及供心保护策略[J].广东医学,2020,41(4):332-335. 被引量：1
-
2罗瑞升,王光,赖增统,黄学彦,陈慧敏.利多卡因在输尿管结石输尿管镜碎石术中缓解输尿管痉挛收缩的应用[J].中国处方药,2022,20(1):125-127.
-
3张敏,王锦平,何勇.利多卡因通过降低微小RNA-181a表达抑制缺氧/复氧诱导的心肌细胞损伤[J].实用临床医药杂志,2024,28(3):68-73.
-
1陈依君,马家骏.几种新型非去极化肌松药用于小儿的初步报告[J].临床麻醉学杂志,1989,5(4):218-220. 被引量：3
-
2史小红,杨建平.术后新斯的明拮抗非去极化肌松药临床观察[J].苏州医学院学报,1999,19(3):337-337.
-
3郭向阳,罗来葵,罗爱伦.非去极化肌松药行快速气管插管的临床应用进展[J].国外医学（麻醉学与复苏分册）,1993,14(6):342-344. 被引量：7
-
4韩传钢,陈益,王力甚.加快非去极化肌松药起效的研究进展[J].医学综述,2011,17(7):1075-1078. 被引量：10
-
5武婷,董培青.极化型心脏停搏液研究进展[J].中华胸心血管外科杂志,2011,27(9):568-570.
-
6陆康生,凌建忠.术前长期使用苯妥英钠对维库溴铵效果影响的临床观察[J].黑龙江医药,2009,22(6):885-886.
-
7薛丽,丁小英,薛荣亮,王国恩.国产维库溴铵肌松效应的临床观察[J].中华综合医学杂志（河北）,2003,5(2):4-5.
-
8薛银珠.维库溴铵前处理对琥珀胆碱的肌颤搐及肌肉松弛效应的影响[J].山西医药杂志（下半月）,2008,37(12):1096-1097.
-
9钟宏,李世康,何魏,冯毅.超极化与去极化保存液对冠状动脉内皮细胞的影响[J].广西医科大学学报,2008,25(4):578-579.
-
10肖亮灿,窦云凌,陈秉学,邓天忠.哌库溴铵预注效果的综合分析[J].临床麻醉学杂志,1998,14(3):39-40. 被引量：3
