摘要
背景:医学生物力学有限元分析的原始资料多为人体CT数据,大范围的CT扫描势必会对人体造成一定的射线伤害。目的:建立兔胫骨骨折三维有限元生物力学模型。方法:选取雄性1年龄新西兰大白兔1只,开放锯断左侧胫骨中段,MIMICS10.01软件直接读取以层厚0.625mm对左侧胫腓骨不间断扫描得到以DICOM3.0格式刻盘保存的CT图片135张,经过定位图像、组织图片、内插值处理以及表面光滑化处理建立面网格模型,导入ANSYS10.0软件构建体并划分体网格,在MIMICS10.01中赋材质。结果与结论:建立了外形和几何结构逼真、生物材料接近正常组织的胫骨中段骨折有限元模型,经加载分析模型真实有效。可见应用MIMICS10.01和ANSYS10.0软件能快速建立兔胫骨骨折三维有限元生物力学模型,为进一步进行实验兔骨折愈合生物力学分析奠定基础。
BACKGROUND： The original data of the medical biomechanics finite element analysis often come from body CT images. Wide range CT scanning can cause damage to human.OBJECTIVE： To establish a three-dimensional finite element model of rabbit tibial fracture,METHODS： A 1-year-old male New Zealand white rabbit was selected, sawing the middle of the left tibia by surgery. Reading the 135-layer of 0.625 mm thick consecutive CT DICOM3.0 format images of rabbit left tibial with the MIMICS10.01 software directly. The surface mesh model was established by images positioning, images organizing, interpolated processing and surface smoothing processing, then the mesh model was introduced into ANSYS10.0 software directly to mesh body, and then transferred the body mesh to MIMICS10.01 for assignment on the basis of CT values.RESULTS AND CONCLUSION： A realistic appearance and calculation accuracy three-dimensional finite element model of rabbit tibial fracture was established. The model was real and effective by applying load and analyzing. The result showed the three-dimensional finite element model of rabbit tibial fracture could be made faster and more accurate by applying MIMICS10.01 software and ANSYS10.0 software. The establishment of the model lays a foundation for rabbit further biomechanical analysis of fracture healing.
出处
《中国组织工程研究》
CAS
CSCD
2013年第4期620-624,共5页
Chinese Journal of Tissue Engineering Research
基金
荆州市科技局课题基金([2010]14号16)
长江大学博士启动基金~~
