主动脉瓣关闭不全与冠状动脉慢血流的临床研究

Exploration of the relationship between Aortic valve insufficiency and coronary slow flow

目的对冠状动脉慢血流病患者主动脉瓣反流和冠脉慢血流之间的关系进行探究。方法2009年2月～2011年8月，根据术前行超声心动图检查的结果，将河南省商丘市第一人民医院105例患者分为主动脉瓣反流组（57例）和无主动脉瓣反流组（48例）。两组患者的年龄、性别、高血压病等基本资料比较差异均无统计学意义（P〉0．05），具有可比性。通过冠状动脉造影排除了严重狭窄方面因素的影响，对患者冠状动脉血流的情况加以观察，并且按照校正TIMI血流的分级方法进行评价和分析。对两组患者慢血流问题发生率以及疾病的程度加以对比。结果主动脉瓣反流组、无主动脉瓣反流组之间的造影校正TIMI帧数差异有高度统计学意义（P〈0．01）。随主动脉瓣反流的严重程度增加，患者的慢血流发生率显著增高。结论主动脉瓣反流患者的冠状动脉慢血流出现的概率会增高。

Objective To explore the relationship between aortic regurgitation and coronary slow flow. Methods The patients in the First People＇s Hospital of Shangqiu City were divided into aortic regurgitation group （57 cases） and non-aorticregurgitation group （48 eases） according to the results of eehoeardiography examation. The general materials of age, sex, hypertension degree had no significant statistics （P 〉 0.05）. Ruled out the influence of serious stenosis fac- tors, the coronary flow degree was observed and assessed with corrected TIMI frame count （CTFC）. Meanwhile, the oc- currence rate and severity of the disease were contrasted. Results The corrected TIMI frame count has statistical sig- nificancc between aortic regurgitation group and non-aorticregurgitation group （P 〈 0.01）. The occurrence rate of slow coronary flow was increasing significantly with the severity of aortic regurgitation. Conclusion The occurrence rate of coronary slow flow is probably increasing in aortic regurgitation patients.