摘要
建立了同时检测化妆品中溴酸盐和碘酸盐的离子色谱-柱后衍生紫外检测器定量分析方法。样品用水提取,经RP柱净化,采用IonPac AS11-HC色谱柱分离,以EG40自动淋洗液发生器生成的KOH为淋洗液梯度洗脱,溴化钾、亚硝酸钠为衍生试剂,二极管阵列检测器检测,外标法定量。结果表明:该方法在2.0~1 000 mg/kg范围内线性关系良好(r≥0.999 8);加标回收率为84%~99%;相对标准偏差小于2%。方法简单、快速、选择性强,可用于化妆品中碘酸盐和溴酸盐的测定。
An ion chromatographic method with post-column deriviation and UV detection for the determination of iodate and bromate in cosmetics was developed and validated. The sample was purified with a guard-column IonPac AG11 - HC (50 mm×4 mm) , and separated on an analytical column IonPac AS11 -HC(250 mm×4 mm) using KOH as an eluent with a self-regeneration suppressor. NaNO2 and KBr were used as the post-column deriviation solution. The analyte was quantitatively analysed by external standard and detected with a DAD detector. The results showed that the calibration curves were linear in the range of 2.0 - 1 000 mg/kg with correlation coefficients not less than 0. 999 8. The spiked recoveries were in the range of 84% - 99% with relative standard deviations ( RSDs, n = 3 ) less than 2% . With advantages of simplicity, good reproducibility and high sensitivity, the method was suitable for the determination of iodate and bromate in cosmetics.
出处
《分析测试学报》
CAS
CSCD
北大核心
2013年第3期385-388,共4页
Journal of Instrumental Analysis
基金
国家质检总局科技计划项目(2011QK143)
关键词
离子色谱法
柱后衍生
化妆品
溴酸盐
碘酸盐
ion chromatography
post-column derivatization
cosmetics
iodate
bromate