心脏术后房颤预防的研究进展
摘要
手术后心房纤颤(Post—operativeatrialfibrilla—tion,POAF)是心脏术后常见并发症,其发生率为30%~50%。并伴随着致病率和病死率的增加,预示着患者有更高的脑卒中危险,需要进一步治疗,增加术后治疗费用。最近研究提示,氧化作用和炎性反应在术后房颤的发生机制中起着主要作用。在预防方面,B-受体阻断剂安全有效,高危患者也可以应用胺碘酮。镁剂,他汀类,N-3多不饱和脂肪酸,皮质类固醇联合B-受体阻断剂可以进一步降低POAF的发生率。本文就这一术后并发症的发生机制及预防的研究进展作一综述。
出处
《医学临床研究》
CAS
2013年第2期349-352,共4页
Journal of Clinical Research
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