RNA干扰技术建立稳定低表达B7-H1的胰腺癌Patu8988细胞株
摘要
B7同源性1(B7Homolog1,B7-H1)分子,亦称为“程序性死亡因子-1配体”(programmed death ligand-1,PD-L1)是T细胞共刺激分子B-7家族成员,肿瘤细胞高表达B7-H1可在多个方面参与肿瘤的免疫逃避过程,研究表明胰腺癌中B7.H1的表达水平与预后呈显著负相关。
出处
《肝胆外科杂志》
2013年第1期65-68,共4页
Journal of Hepatobiliary Surgery
基金
国家自然科学基金资助项目(81001138)
江苏省普通高校研究生科研创新计划资助项目(CXZZ11_0125)
苏州市科技计划资助项目(SYS201120)
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