ICU抗菌药物耐药与临床药学监护

Clinical Pharmaceutical Care to Antibiotic Drug Resistance in Intensive Care Unit

临床药师可以积极参与到重症监护室(Intensive care unit,ICU)抗菌药物临床药学监护中,尤其针对抗菌药物的耐药。临床药师可通过专业优势在药代动力学、药效动力学参数规范抗菌药物的使用并提供个体化给药方案。也可以通过监督抗菌药物轮换使用的方式减少耐药率的发生。临床药师可以与感染控制科一同监测ICU抗菌药物耐药率。并监督预防感染疫苗的使用。定期收集抗菌药物使用相关指标可以使临床药师更容易掌握耐药率情况,并通过多种渠道与临床医务人员及时沟通,有效控制ICU患者抗菌药物耐药情况。

Clinical pharmacist can play an important role to administer antibiotic use in intensive care unit, especially in the antibiotic drug resistance. Clinical pharmacist can provide personalized dosage regimen through pharmacokinetics and pharmacodynamics parameter. Clinical pharmacist can also decrease antibiotic drug resistance through monitoring the rotation of the drug. Clinical pharmacist can monitor antibiotic drug resistance rate cooperate with infection control department, and clinical pharmacist can monitor the vaccines to prevent infection. Regular collection of antibiotics using index can easily control drug resistance rate, and on time connection to clinical staffs can effectively control antibiotic drug resistance in intensive care unit.