血清肺肿瘤抗原检测对肺癌诊断的价值

Evaluation of lung tumor antigen in serum for the diagnosis of lungs cancer

目的探讨一种敏感的肺癌辅助诊断方法。方法采用乳胶凝集法对 144例良、恶性肺部疾病患者和 2 8例健康人血清肺肿瘤抗原 (LTA)进行检测。结果肺癌组阳性率 78.3 % ,对照组阳性率 7.6 % ,差异有非常显著意义 (P <0 .0 1) ;其中非小细胞肺癌阳性率 88.2 % ,小细胞肺癌阳性率7.7% ,差异亦有非常显著意义 (P <0 .0 1)。肺癌组中包括 2例原位癌患者 ,血清LTA检测均呈阳性 ,说明血清LTA检测有助于早期肺癌的发现。结论血清LTA检测是一种快速、简便、敏感的肺癌 (尤其是非小细胞肺癌 )辅助诊断方法。

Objective To explore a sensitive method for the diagnosis lungs cancer. Methods The lung tumor antigen(LTA) of 144 cases from benign and malignant tumor of lung and 28 health peoples as control in the serum samples were measured by the gel coagulatic assay. Results The lung lung cancer group that positive rate of LTA was 78.3%,the control group was 7.6%( P<0.01 )Among those lungs cancer cases wer non-small cellular cancer for 88.2%, and small cellular cancerfor7.7%( P<0.01 ). Two cases were lungs carcinoma in situ and LTA for positive. The confiirmed that serum LTA test was helpful for diagnosis of early stage lung cancer. Conclusion Test of LTA was a fast, simple, sensitive method for the diagnosis of lungs cancer.