盐酸利托君与硫酸镁治疗先兆早产的疗效对比观察

目的对比观察盐酸利托君与硫酸镁治疗先兆早产的临床疗效。方法选取2008年5月～2012年4月武冈市妇幼保健院收治的先兆早产患者83例为研究对象,随机分为两组。对照组42例,给予硫酸镁治疗;观察组41例,给予盐酸利托君治疗。比较两组孕妇的孕龄延长时间、不良反应发生率、新生儿存活率、出生体重以及Apgar评分的差异。结果与对照组比较,观察组孕妇的孕龄延长时间较长,为(29.12±4.02)d,新生儿存活率较高(97.56%),治疗期间不良反应发生率较低(7.32%),组间比较差异有统计学意义(P<0.05)。观察组新生儿存活率、出生体重以及Apgar评分均明显高于对照组,组间比较差异显著,有统计学意义(P<0.05)。结论采用盐酸利托君治疗先兆早产的临床疗效优于硫酸镁,且不良反应较轻微,孕妇孕期延长,新生儿存活率高,值得临床推广应用。

Objective To compare the observed ritodrine hydrochloride and magnesium sulfate in the treatment of threatened preterm labor differences in efficacy for the clinical to reference and learn.Methods Chose the 83 cases of threatened preterm labor patients for the study from May 2008 to April 2012,and grouping at random. Use magnesium sulfate to do the treatment for the 42 patients from the control group,and use ritodrine hydrochloride to do the treatment for the 41 patients the observation group. Extend the gestational age of the observed and compared two groups of pregnant women,differences in neonatal survival and incidence of adverse reactions. Results Compared with the control group,the gestational age of the pregnant women from the observation group to extend longer （29.12 ± 4.02） d,and the neonatal had a higher survival rate （92.68%）,the incidence of adverse reactions during treatment is lower than the control group （7.32%）,data by the statistical analysis,the difference was statistically significant （P0.05）. Conclusion The Clinical efficacy of using ritodrine hydrochloride to do the treament of threatened preterm labor is better than using magnesium sulfate,it can extend the pregnancies and improve the neonatal survival, in addition the adverse reactions are mild,which should be widely applied.