期刊文献+

二甲双胍联合质子泵抑制剂治疗2型糖尿病的疗效观察 被引量:13

二甲双胍联合质子泵抑制剂治疗2型糖尿病的疗效观察
下载PDF
导出
摘要 目的研究和探讨二甲双胍联合质子泵抑制剂治疗2型糖尿病的临床效果。方法将2012年3月~2012年9月收治的62例2型糖尿病患者进行随机分组,每组各31例。其中,研究组给予二甲双胍联合质子泵抑制剂治疗,对照组给予二甲双胍治疗。对两组临床治疗效果进行观察和比较。结果经过6个月治疗后,研究组31例患者的FPG、P2hBG、FINS、P2hINS均优于对照组,差异具有统计学意义(P<0.05)。结论二甲双胍联合质子泵抑制剂治疗2型糖尿病,临床效果稳定,降糖效果明显。 Objective to study and discuss metformin joint proton pump inhibitor of treatment for type 2 diabetes clinical effect. Methods From March 2012 to september 2012 patients of 62 cases of type 2 diabetes mellitus patients with random group, each group of 31 cases. Among them the team metformin joint proton pump inhibitor treatment group, take metformin treatment. The two group of clinical treatment effect were observed and compared. Results After six months of treatment, the team and patients of FPG and P2hBG, FINS, P2hINS is better than control group, a statistically significant difference (P0.05).Conclusion Metformin joint proton pump inhibitor of treatment for type 2 diabetes, clinical effect stable, hypoglycemic effect is obvious.
出处 《当代医学》 2013年第8期32-33,共2页 Contemporary Medicine
关键词 二甲双胍 质子泵抑制剂 2型糖尿病 临床 Metformin Proton pump inhibitor Type 2 diabetes Clinical
  • 相关文献

参考文献6

二级参考文献30

  • 1华文进,韩勤芬,陈慧,薛俊.马来酸罗格列酮联合格列美脲、二甲双胍治疗2型糖尿病的疗效观察[J].中国糖尿病杂志,2007,15(1):10-11. 被引量:14
  • 2张惠芬.实用糖尿病学.人民卫生出版社.2001:370.
  • 3Day C. Thiazolidinediones:a new class of antidiabetic drugs. Diabet Med, 1999,16 (3) : 179-192.
  • 4Kunogi Y. Mesangia cell proliferation inhibitors for the treatment of prolifcrativc glomerular disease. Med Res Rev, 2003,23 : 15 -31.
  • 5Lebovitz H E ,Dole J E ,Patwardhan R ,et al. Rosiglitazone monotherapy is effective in patients with type 2 diabetes [J].J ClinEndocrinol Metab, 2001,86 : 280- 288.
  • 6Bretzel RG,Voigt K,Schatz H.The United Kingdom Prospective Diabetes Study(UKPDS) implications for the pharmacotherapy of type 2 diabetes mellitus[J].Exp Clin Endocrinol Diabetes,1998;106:369.372.
  • 7Lehmann JM,Moore LB,Smith-Oliver TA,et al.An antidiabetic th-iazolidinedione is a hish affinity ligand for peroxisome proliforactor-activated receptorγ[J].J Biol Chem,1995;270:129-153.
  • 8Rodriguez A,Reviriego J,Polavieja P,et al.Six-month effectiveness and tolerability of pioglitazone in combination with sulfonylureas or metformin for the treatment of type 2 diabetes mellitus[J].Med Clin,2008;131:721-730.
  • 9Otto M,Breinholt J,Westergaard N.Metformin inhibits glycogen synthesis and gluconeogenesis in cultured rat hepatocytes[J].Diabe-tes Obes Metab,2003;5:189-194.
  • 10Kahn CR,Banting lecture.Insulin action diahetogenes and the cause of type 2 diabetes[J].Diabetes,1994,43:1066-1084.

共引文献85

同被引文献55

引证文献13

二级引证文献42

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部