莫西沙星与左氧氟沙星治疗社区获得性肺炎的对比分析

Clinical analysis on efficacy of moxifloxacin and levofloxacin in treatment of community acquired pneumonia

目的对比观察莫西沙星与左氧氟沙星治疗社区获得性肺炎的临床疗效。方法分析收治的社区获得性肺炎患者临床资料,依据治疗方式不同分为莫西沙星组30例和左氧氟沙星组30例。结果莫西沙星组咳嗽消失时间、体温恢复正常时间、血常规恢复时间、胸部阴影明显吸收>50%时间均低于左氧氟沙星组,莫西沙星组细菌清除率和临床治疗总有效率均明显优于左氧氟沙星组,差异均有统计学意义(P<0.05)。结论莫西沙星治疗社区获得性肺炎临床症状改善明显,效果优于左氧左氧氟沙星,值得临床推广应用。

Objective To explore the efficacy of moxifloxacin and levofloxacin in treatment of community acquired pneumonia. Methods The clinical data of patients with community acquired pneumonia were collected, and they were divided into moxifloxacin group （30 cases） and levofloxacin group （30 cases）. Results The duration for disappearance of coughing, defervescent time, normalized time for blood routine exami- nation, and time for X - ray lung shadow apparent absorption 〉 50% in patients of moxifloxacin group were lower than those of patients in levoflox- acin group, the total effectiveness rate of clinical cure in patients of moxifloxacin group was higher than that of patients in levofloxaein group. The rate of bacterial clearance in patients of moxifloxacin group was better than that of patients in levofloxacin group, and their difference was statistical- ly significant （ P 〈 0.05 ）. Conclusion The clinical efficacy of moxifloxacin in treatment of community acquired pneumonia is obviously better than that of levofloxacin, and it is worthy to be recommended for clinical application.