摘要
目的:观察滋阴清热法治疗咳嗽变异性哮喘的临床疗效。方法:将84例咳嗽变异性哮喘患者,随机分为2组,治疗组予滋阴清热方(黄芩、麦冬、知母、沙参等,1剂,早晚分服);对照组予茶碱缓释胶囊(100 mg/次,日2次),4周为1疗程。观察2组的临床疗效、咳嗽缓解和消失时间及治疗前后外周血IFN-γ、IL-4水平。结果:治疗组总有效率95.24%,明显高于对照组(78.57%),2组比较,有统计学意义(P<0.05);治疗组治疗后IFN-γ和IL-4因子较治疗前明显改善(P<0.01);治疗组治疗后IFN-γ和IL-4和对照组治疗后比较,有统计学意义(P<0.01或0.05);治疗组咳嗽缓解和消失时间较对照组明显改善,2组比较,有统计学意义(P<0.01)。结论:滋阴清热法治疗咳嗽变异性哮喘疗效较好,值得临床推广应用。
Objective:To study the therapeutic effect of nourishing yin and clearing heat method on patients with cough variant asthma(CVA). Methods: 84 patients with CVA in our department were divided into two groups randomly. Patients in the group A were treated with nourishing yin and clearing heat method, the group B were treated with theophylline sustained- release capsules only. The clinical effect, the IFN-y and IL-4 levels, the time of cough relief and disappearance of the two groups were compared. Results: The excellent rate of the group A was 95.24%, which was significantly higher than the group B 78.57 % ( P 〈 0.05) ; the level of 1FN-y or IL-4 level in group A was significantly different before and after treat- ment, which was also significantly between the two groups after the treatment( P 〈 0.01 or 0.05) ;the time of cough relief and disappearance were significantly different between the two groups (P 〈 0.01 ). Conclusion: Nourishing yin and clearing heat method is a safe and efficient treatment method of patients with CVA, it is worthy of clinical implication.
出处
《吉林中医药》
2013年第2期154-155,共2页
Jilin Journal of Chinese Medicine