异丙酚氯胺酮在儿童声带息肉切除术中的比较

Comparison of Propofol and Ketamine in the Resection of Polyp of Vocal Cord in Children

目的 :探讨儿童声带息肉的适宜麻醉方式。方法 :12 4例声带息肉患儿随机分为两组 ,每组 62例。分别静脉注射异丙酚 2mg kg及氯胺酮 2mg kg(两组均辅以咪唑安定 0 .1mg kg静脉注射 ) ,观察比较两组起效时间、恢复时间及对循环、呼吸系统的影响 ,所有数据用t检验进行统计处理。结果 :两组麻醉方式均能顺利完成手术。与氯胺酮组相比 ,异丙酚组起效快 ,苏醒质量高 ,但对循环、呼吸系统有一定的抑制作用。结论 :对于无明显心、肺疾病的声带息肉患儿 ,选择异丙酚麻醉效果更佳 ,但应加强对呼吸、循环系统的监测。

Objective:To investigate the optimal anesthesia for the resection of polyp of vocal cord in children. Method:124 patients were randomly divided into two groups; propofol group (n=64, intravenously giving propofol 2 mg/kg) and ketamine group (n=64, intravenously giving ketamine 2 mg/kg). Both groups were induced by intravenous infusion of midazolam 0.1 mg/kg before anesthesia. Initiating time of result and time of recovery, effects of drugs on the respiratory and circulatory systems were observed and compared. All data were statistically treated by t test. Results:Anesthesia could be smoothly completed in both propofol group and ketamine group. Comparing with ketamine, propofol could rapidly take effect of anesthesia, and more improve the quality of recovery of consciousness. However, propofol could occur depression in the respiratory and circulatory systems in some cases. Conclusion:In the pediatric polyp of vocal cord without significant cardiac and pulmonary disease, propofol is superior to ketamine as an anesthesia agent, in the meantime, it is necessary to monitor the respiratory and circulatory systems.