HASTE与HASTE-IR序列对肝实质病灶的对比性研究

A Comparison of HASTE and HASTE-IR Sequence for Detection of Hepatic Lesions

目的 评价屏气下T2 WIHASTE与HASTE IR序列对肝癌的检测能力。材料与方法 6 2例肝脏肿瘤患者进行了屏气下HASTE和HASTE IR序列T2 WI。同一层面的成像采用上述 2种序列进行分析 ,记录平均信号强度和标准差。肝脏、脾脏及肿瘤的信噪比 (SNR)和相对对比噪声比 (rCNR)通过除以背景噪声的标准差后进行统计学分析。结果 HASTE IR序列显示病灶与肝实质的对比度高 ,图像清晰。肿瘤 /肝实质和脾脏 /肝实质的rCNR分别为HASTE IR序列 :1.2 1± 0 .2 4,1.74± 0 .2 5 ;HASTE序列 :0 .71±0 .0 7,0 .75± 0 .18,两者之间有显著性差异 (t=1.94,2 .35 ;P =0 .0 3 <0 .0 5 )。另外 ,HASTE IR序列发现了 12个 (19.4% )HASTE序列无法显示的小病灶。结论 屏气下HASTE IR序列和HASTE序列对肝脏实质性病灶均具有较高的敏感性 ,但前者显示肿瘤 /肝实质的rCNR明显高于后者 。

Objective To evaluate breath holding T 2WI techniques (HASTE, HASTE IR) in detecting liver cancer.Materials and Methods Sixty two patients with liver cancer underwent T 2WI HASTE and HASTE IR. Images of the same anatomic slice obtained from the two sequences were compared. Mean signal intensity and standard deviation were recorded. Signal to noise ratios for liver, spleen and focal lesions were obtained through dividing the mean signal intensity by standard deviation of background noise. Contrast to noise ratios were obtained through dividing the absolute value of the liver lesion signal intensity difference by standard deviation of background noise.Results Liver SNR, spleen SNR, solid lesion relative CNR and spleen relative CNR for HASTE were 25.2±1.9, 39.7±5.4, 0.71±0.07 and 0.75±0.18, respectively, while for HASTE IR were 12.8±2.3, 25.2±7.5, 1.21±0.24 and 1.74±0.25, respectively. HASTE was inferior to HASTE IR in detecting solid liver lesions (t=1.94,2.35; P=0.03<0.05). Twelve smaller solid liver lesions were discovered on HASTE IR sequence, but could not display on HASTE sequence.Conclusion Though both breath holding HASTE sequence and HASTE IR sequence have high sensitivity in detecting solid liver lesion, HASTE IR is more sensitive than HASTE. HASTE IR may be served as one of the T 2WI conventional imaging.