2Jonsson M K, Wahren B. Sexually transmitted herpes simplex viruses [J].Scand J Infect Dis, 2004, 201 (36):93-101.
3Vanghan T, Osboum J K, Tempest P R,et al. Human antibodies by design [J].Nature Biotechnol, 1998,16(2) :535-539.
4Marks J D, Hoogenboom H R, Bonnert T P, et al. By passing immunization:Human antibodies form V-gene libraries displayed on phage [J]. J Mol Biol,1991, 222(3) :581-597.
5Verma R, Boleti E, George A J. Antibody engineering: comparison of bacterial,yeast, insect and mammalian expression systems [J]. J Immunol Methods, 1998,216( 1 ) : 165-181.
6Hoogenboom H R, Griffiths A D, Johnson K S, et al. Multi-subunit proteins on the surface of filamenatous phage methodologies for displaying antibody(Fab) heavy and light chains [J]. Nucleic Acids Res, 1991,19(15) :4133-4137.
7Tang Y, Jiang N, Parakkh C, et al.Selection of linkers for acatalytic single-chain antibody using phage display technology [J]. J Biol Chem, 1996,271(26) : 15682-15687.
8Turner D J, Ritter M A, George A J, et al. Importance of the linker in expression of single-chain Fv antibody fragments:optimisation of peptide sequence using phage display technology [ J ]. Immunol Method, 1997,205 ( 1 ) : 43-54.
9Kipriyanov S M, Moldenhaner G, Little M, et al. High level production of soluble single chain ant- ibodies in small-scale Escherichia coli cultures [J]. J Immunol Methods, 1997, 200(1-2) :69-77.
10Eldin P, Pauza M E, Hieda Y, et al. High-level secretion of two antibody single chain Fv fragment s by Pichiapastoris [J]. J Immunol Methods, 1997,201 ( 1 ) : 67-75.