生精片联合左卡尼汀治疗特发性少弱精子症的临床观察

Clinical observation of spermatogenic tablet combined with levocarnitine therapy for idiopathic oligospermia and asthenospermia

目的观察生精片联合左卡尼汀治疗特发性少弱精子症的疗效。方法收集特发性少弱精子症120例,随机分为A组(生精片组)、B组(左卡尼汀组)和C组(联合组)。连续服用3个月后观察治疗效果。结果除B组有2例退出外,其余118例均完成治疗。A组精液密度、活力较治疗前有明显的变化(P<0.05),活率变化不大(P>0.05);B组精子活率较治疗前明显增加(P<0.05),精子密度变化不大(P>0.05);C组精液密度、活力及活率较治疗前增加(P<0.05)。C组较A、B两组在治疗后的精液活率、活力及密度方面变化显著(P<0.05)。A、B两组间比较无明显变化。结论生精片联合左卡尼汀对改善精子密度、活力及活率临床效果明显,具有一定的应用前景。

Objective To observe the effect of spermatogenic tablet combined with levocarnitine therapy for idiopathic oligospermia and asthenospermia. Methods Collection of idiopathic oligospermia and asthenospermia 120 cases, were randomly divided into group A （spermatogenic slice group）; group B （L-carnitine group）; group C （combined group）. Observation on therapeutic effect of continuous administration of 3 months. Results 2 cases in group B withdrawal, the remaining 118 patients completed treatment, group A： semen density, energy markedly changes （P 〈 0.05）. Survival rate of change （P 〉 0.05）. Group B： sperm activity rate significantly increased （P 〈 0.05）, sperm density change （P 〉 0.05）. Group C sperm density, motility and survival rate of increase than before treatment （P〈 0.05）. Group C and A, B in the two groups after treatment of sperm viability, motility and density changes significantly （P 〈 0.05）. A, B between the two groups showed no significant change. Conclusion Spermatogenic tablet combined with levocarnitine on sperm density, motility and viability has certain application prospect in idiopathic oligospermia and asthenospermia.