炎宁冲剂的抗炎与解热作用研究

Studies on the anti inflammatory and antipyretic effects of Yanning Granules

目的 :研究炎宁冲剂的抗炎与解热作用。方法 :采用角叉菜胶致大鼠足跖炎性肿胀 ,二甲苯致小鼠耳毛细血管通透性增高 ,以及大鼠皮下羧甲基纤维素囊中白细胞游出等急性炎症模型研究炎宁冲剂的抗炎作用 ;采用啤酒酵母液引起家兔发热的方法研究炎宁冲剂的解热作用。结果 :炎宁冲剂对以上实验动物均具有明显的抗炎和解热作用。结论 :炎宁冲剂对急性炎症具有明显的抗炎作用 。

OBJECTIVE:To study the anti inflammatory and antipyretic effects of Yanning Granules(YNG).METHOD:Inflammatory foot pad swelling caused by carrageenin in rats,increasing of capillary permeability of mouse ears caused by dimethylbenzene,and leukocytoplania from the subcutaneous CMC Na cysts of rats were used to study the anti inflammatory effect of YNG.Fever induced by brewer′s yeast in rabbits was used to study the antipyretic effect of YNG.RESULTS:YNG markedly inhibited the reaction of acute inflammation and fever in the model animals.CONCLUSION:YNG was proved having significant anti inflammatory and antipyretic effects.