52例早产儿颅内出血相关因素分析

Related Factors Analysis of 52 Premature Infants of Intracranial Hemorrhage

目的:探讨早产儿颅内出血发生的危险因素。方法:本研究分观察组和对照组,选取本院自2009年1月2012年1月新生儿重症监护病房(NICU)收治的221例的早产儿,其中颅内出血52例作为观察组,其余未发生颅内出血的早产儿169例作为对照组,回顾性分析早产儿颅内出血发生的危险因素。结果:对ICH组和对照组的产前异常因素进行比较,宫内窘迫、羊水异常、妊高征、前置胎盘、脐带异常、是否预防应用苯巴比妥钠差异有统计学意义(P<0.05);ICH组和对照组新生儿出生时的异常因素的比较,与Apgar评分、出生体重、胎龄差异有统计学意义(P<0.05)。结论:早产儿颅内出血的发生可能与宫内窘迫、羊水异常、妊高征、前置胎盘、脐带异常、是否预防应用苯巴比妥钠以及Apgar评分、出生体重和胎龄有关。

Objective：To investigate the cause of intracranial hemorrhage（ICH） in premature infants associated risk factors.Methods：Research points trial group and control group,the objects in our hospital the neonatal intensie care unit（NICU） of 221 cases were premature from January 2009 to January 2011.52 cases of intracranial bleeding as research group,the rest of the 169 cases of premature infants as control group,retrospective analysis of premature intracranial bleeding risk factors.Results：ICH group and control group for comparison of prenatal abnormal factors,palace distress,amniotic fluid anomaly,pregnancy hypertension sickness,lead the placenta,the umbilical unusual cord,Phenobarbital Sodium,the difference was statistically significant（P0.05）;ICH group and control group premature birth risk factors comparison with Apgar score,birth weight,gestational age,the difference was statistically significant（P0.05）.Conclusion：Premature infants＇ intracranial hemorrhage may be with palace distress,amniotic fluid anomaly,pregnancy and high blood pressure,lead the placenta,an umbilical cord,Phenobarbital Sodium and Apgar score,birth weight and the gestational age.