C反应蛋白(CRP)和同型半胱氨酸(HCY)对冠心病冠脉损伤的预测价值

The Prediction Value of CReactive Protein (CRP) and Homocysteine (HCY) for Coronary Injury in Coronary Heart Disease

目的:探讨CRP和HCY在冠心病冠脉损伤中的检测价值。方法:选取60例冠心病患者及同期健康体检者40例(正常组)为研究对象,测定两组的CRP、HCY水平,分析CRP、HCY与冠脉损伤的相关性。结果:冠心病组的CRP、HCY显著高于正常组(P<0.05)。随着病情的加重,SAP组、UAP组、AMI组的CRP、HCY逐渐升高,各组之间有显著性差异(P<0.05)。随着病变支数的增加,单支病变组、双支病变组、多支病变组的的CRP、HCY而升高,各组之间有显著性差异(P<0.05)。且病变支数与CRP、HCY呈正相关(P<0.05),CRP与HCY呈正相关(P<0.05)。结论:冠心病患者CRP、HCY显著升高,且病情越重升高越明显,考虑两者可能共同参与了冠状动脉的病变过程,可作为预测冠脉风险的独立评价指标。

Objective：To investigate the prediction value of CRP and HCY for coronary injury in coronary heart disease.Methods：60 cases of patients with coronary artery disease and 40 cases of concomitant health examination（normal group） were chosen as the research object,the two groups were measured of CRP HCY and analysis of the correlation between CRP HCY coronary artery injury.Results：HCY CRP in coronary heart disease group was significantly higher than that in normal group（P0.05）.With the aggravation of the disease,CRP,HCY in SAP group,UAP group,AMI group were gradually increased,there was significant difference between the groups（P0.05）.As the lesion count increases,HCY and CRP in single vessel disease group double vessel lesion group,multivessel disease group were increased,there was significant difference between the groups（P0.05）.And lesion vessels and CRP,HCY were positively correlated（P0.05）,CRP was positively correlated with HCY（P0.05）.Conclusion：CRP,HCY in coronary heart disease are increased significantly and the higher,the more serious it is they may participate in coronary artery disease process that can be used as a predictor of coronary risk independent evaluation index.