宫颈癌盆腔淋巴结转移相关因素的分析

Risk Factor of Node Metastasis in Cervical Carcinoma

探讨Ⅰ、Ⅱ期宫颈癌淋巴结转移相关因素。回顾性地分析590例行广泛性全子宫切除及盆腔淋巴结清扫术的Ⅰ、Ⅱ期宫颈癌患者的临床分期及病理资料。将盆腔淋巴结转移与各临床参数的关系进行统计学分析。结果Ⅰ、Ⅱ期宫颈癌盆腔淋巴结总的转移率为20.34%,年龄、临床分期、肿瘤直径、肿瘤生长方式、肿瘤组织学分级、肌层浸润深度、脉管浸润、阴道切缘受累均与盆腔淋巴结转移相关,而病理类型、术前放化疗与盆腔淋巴结转移无关。结论:年龄越轻,临床期别越晚,肿瘤直径越大,浸润深度越深,溃疡型肿瘤病理分化越差,阴道切缘受累,伴有脉管浸润者,盆腔淋巴结转移率就越高。

To investigate the relative factors of pelvic lymph nodes metastasis in patients with cervical carcinoma of stage Ⅰ and Ⅱ. the clinical and pathological information of 590 patients with cervical carcinoma of stage Ⅰ and Ⅱ after radical hysterectomy with lymphadenectomy were retrospectively analyzed. The correlation between the clinico-pathologic findings and the situation of pelvic lymph nodes metastasis was statistically analyzed. It is resulted that pelvic lymph nodes metastasis rate was 20. 34%, age, clinical stage, tumor size, tumor growth type, pathological grade, myometrial invasion, vessel invasion and vaginal margin were related to the pelvic lymph nodes metastasis and no significant difference was found in pathlogical category and preoperative radiotherapy and chemotherapy. So： the more young age, lated stage, greater tumor diameter , deeper myometrial invasion , ulcerative type , worse in pathological grade, vaginal margin and vessel invasion, the higher pelvic lymph node metastasis rate.